trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid
CAS: 2227662-58-8
Molecular Formula: C13H16O2
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid - Names and Identifiers
| Name | trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid |
| Synonyms | trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid |
| CAS | 2227662-58-8 |
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C13H16O2 |
| Molar Mass | 204.26 |
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid - Introduction
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid is an organic compound with the chemical formula C13H16O2.
The compound has the following properties:
-Appearance: White solid
-Melting point: about 96-98 ° C
-Solubility: Soluble in ethanol, ether and dichloromethane and other organic solvents, insoluble in water.
-Stability: relatively stable at room temperature, but may react when encountering strong oxidants.
The main uses of trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid are as follows:
-As a pharmaceutical intermediate: The compound can be used in synthetic drugs, biologically active compounds and pharmaceutical research.
-Organic synthesis: as a reagent and catalyst in the field of organic synthesis.
The method of preparing trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid usually includes the following steps:
1. Put p-diisopropyl benzene and ethylene dimethylcyclopropane in a solvent containing a catalyst (such as aluminum trichloride), and perform a cyclopropanation reaction at an appropriate temperature.
2. After the reaction is completed, trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid is obtained by hydrolysis and acidification treatment.
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid is relatively safe to the human body and the environment under general conditions of use. However, as organic compounds, operators should follow appropriate laboratory safety practices, including wearing appropriate personal protective equipment (e. G., lab gloves, goggles, etc.) and avoiding inhalation, contact, and ingestion.
The compound has the following properties:
-Appearance: White solid
-Melting point: about 96-98 ° C
-Solubility: Soluble in ethanol, ether and dichloromethane and other organic solvents, insoluble in water.
-Stability: relatively stable at room temperature, but may react when encountering strong oxidants.
The main uses of trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid are as follows:
-As a pharmaceutical intermediate: The compound can be used in synthetic drugs, biologically active compounds and pharmaceutical research.
-Organic synthesis: as a reagent and catalyst in the field of organic synthesis.
The method of preparing trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid usually includes the following steps:
1. Put p-diisopropyl benzene and ethylene dimethylcyclopropane in a solvent containing a catalyst (such as aluminum trichloride), and perform a cyclopropanation reaction at an appropriate temperature.
2. After the reaction is completed, trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid is obtained by hydrolysis and acidification treatment.
trans-2-(2-isopropylphenyl)cyclopropane-1-carboxylic acid is relatively safe to the human body and the environment under general conditions of use. However, as organic compounds, operators should follow appropriate laboratory safety practices, including wearing appropriate personal protective equipment (e. G., lab gloves, goggles, etc.) and avoiding inhalation, contact, and ingestion.
Last Update：2024-04-09 20:45:29
