trans-2-(4-broMophenyl)cyclopropanecarboxylic acid - Names and Identifiers
trans-2-(4-broMophenyl)cyclopropanecarboxylic acid - Physico-chemical Properties
Molecular Formula | C10H9BrO2
|
Molar Mass | 241.08126 |
Storage Condition | Room Temprature |
trans-2-(4-broMophenyl)cyclopropanecarboxylic acid - Introduction
(1S,2S)-2-(4-broMophenyl) cyclopropecarboxylic acid is an organic compound with the chemical formula C10H9BrO2. Here is some information about the compound:
Nature:
-Appearance: White solid
-Melting point: 109-111 degrees Celsius
-Solubility: Soluble in organic solvents
Use:
- (1S,2S)-2-(4-broMophenyl)cyclopropanecarboxylic acid is a chiral compound, which can be used as a chiral drug, intermediates and ligands of organic synthesis are used in metal-catalyzed reactions and other applications.
Method:
(1S,2S)-2-(4-broMophenyl) cyclopropylecarboxylic acid can be synthesized by the following steps:
1. (1S,2S)-cyclopropanedicarbonitrile ((1S,2S)-cyclopropane-1,2-dicarboxylic acid) with 4-bromobenzenboronic acid (4-bromobenzenboronic acid) in sodium hydride (NaH) catalytic reaction to generate (1S,2S)-2-(4-bromophenyl) cyclopropane dicarbonitrile.
2. The above dicarbonitrile is reacted with water and acetic acid to obtain (1S,2S)-2-(4-broMophenyl)cyclopropanecarboxylic acid.
Safety Information:
The safety data of- (1S,2S)-2-(4-broMophenyl)cyclopropanecarboxylic acid are limited. Therefore, laboratory safety procedures should be followed in handling and storage, and contact with skin should be avoided, eye and inhalation.
-Wear appropriate protective equipment such as lab gloves, goggles, and lab coats when handling the compound.
-Waste must be disposed of in accordance with local regulations to avoid environmental and health hazards.
Last Update:2024-04-09 20:49:11