Penduletin MedChemExpress (MCE)

Product Name	Penduletin
Synonyms	Penduletin 3,6,7-Trimethyl-6-hydroxykaempferol 5,4'-Dihydroxy-3,6,7-trimethoxyflavone 6-Hydroxykaempferol 3,6,7-trimethyl ether 5-hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxychromen-4-one 5-Hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one Synonyms Penduletin 3,6,7-Trimethyl-6-hydroxykaempferol 5,4'-Dihydroxy-3,6,7-trimethoxyflavone 6-Hydroxykaempferol 3,6,7-trimethyl ether 5-hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxychromen-4-one 5-Hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-3,6,7-trimethoxy-
CAS	569-80-2
EINECS
Chemical Formula	C18H16O7
Molecular Weight	344.32
inchi
Package	1 mg
Price	Email to quote
Descriptions	Penduletin Penduletin MedChemExpress (MCE) HY-N3096 569-80-2 99.59% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Penduletin Penduletin MedChemExpress (MCE) HY-N3096 569-80-2 99.59% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Penduletin is a flavone, that can be isolated from Brickelia pendula and Vitex negundo. Penduletin shows anticancer activity. Penduletin induces apoptosis in the cancer cells through ROS generation. Penduletin (0-100 µg/mL, 48 h) shows antiproliferative activity against HepG2 and MCF-7 cell lines, with IC50 values of 25.8, and 6.4 µM, respectively[1]. Penduletin exhibits an enhanced ability to induce the cleavage of procaspase‐3 in HepG2 and both procaspase‐3 and procaspase‐8 in MCF-7 cells line[1]. \| \| \| \| \| \| \| \| \| \| [1]. Flores S E, et al.The structure of pendulin and penduletin: a new flavonol glucoside isolated from brickelia pendula[J].Tetrahedron, 1958, 2(3-4):308-315. [2]. Vo GV, et al. In silico and in vitro studies on the anti-cancer activity of artemetin, vitexicarpin and penduletin compounds from Vitex negundo. Saudi Pharm J. 2022 Sep 30(9):1301-1314. [Content Brief]
Last Update	2025-04-01 14:45:47

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