Ocrelizumab MedChemExpress (MCE)

Product Name	Ocrelizumab
Synonyms	Ocrelizumab;Research Grade Ocrelizumab(DHC90702)
CAS	637334-45-3
EINECS
Chemical Formula	C19H16N2O5
Molecular Weight
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Ocrelizumab Ocrelizumab MedChemExpress (MCE) HY-P9960 637334-45-3 95.00% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Ocrelizumab (Ocrevus) is a humanized anti-CD20 monoclonal antibody. Ocrelizumab can induce B cell depletion and inhibit multiple sclerosis lesions in mice through antibody dependent cytotoxicity (ADCC). Ocrelizumab (7.5 mg/kg Descriptions Ocrelizumab Ocrelizumab MedChemExpress (MCE) HY-P9960 637334-45-3 95.00% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Ocrelizumab (Ocrevus) is a humanized anti-CD20 monoclonal antibody. Ocrelizumab can induce B cell depletion and inhibit multiple sclerosis lesions in mice through antibody dependent cytotoxicity (ADCC). Ocrelizumab (7.5 mg/kg once daily 18 days s.c. or i.v.) inhibits lesions in multiple sclerosis mice by inducing B cell exhaustion through antibody dependent cytotoxicity (ADCC)[1]. Ocrelizumab (50 μg repeat administration on days 7, 14, and 21 i.v.) can reduce B and T cells in the blood, lymph nodes, and spleen of C57BL/6 mice[2]. \| \| \| \| \| \| \| \| \| \| [1]. Torres JB, et al. Distribution and efficacy of ofatumumab and ocrelizumab in humanized CD20 mice following subcutaneous or intravenous administration. Front Immunol. 2022 Jul 28 13:814064. [Content Brief] [2]. Schubart A, et al. Effect of Subcutaneous vs Intravenous Chronic Treatment with an Anti-CD20 Antibody on B-, T-and Myeloid Lymphocyte Subsets in Blood, Lymph Nodes and Spleen of C57BL/6 Mice (P2. 410)[J]. Neurology, 2018, 90(15_supplement): P2. 410.
Last Update	2025-04-01 14:45:47

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