Daratumumab (PBS) MedChemExpress (MCE)

Product Name	Daratumumab
Synonyms	Daratumumab
CAS	945721-28-8
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Daratumumab (PBS) Daratumumab (PBS) MedChemExpress (MCE) HY-P9915A 945721-28-8 Anti-Human CD38, Human Antibody (PBS) 95.0% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Daratumumab (PBS) (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab (PBS) has anti-multiple myeloma (MM) effect. Daratumumab (PBS) impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition. Daratumumab (Anti-Human CD38) induces potent Ab-dependent cellular cytotoxicity in CD38-expressing lymphoma- and MM-derived cell lines[2]. Daratumumab (i.p. Descriptions Daratumumab (PBS) Daratumumab (PBS) MedChemExpress (MCE) HY-P9915A 945721-28-8 Anti-Human CD38, Human Antibody (PBS) 95.0% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Daratumumab (PBS) (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab (PBS) has anti-multiple myeloma (MM) effect. Daratumumab (PBS) impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition. Daratumumab (Anti-Human CD38) induces potent Ab-dependent cellular cytotoxicity in CD38-expressing lymphoma- and MM-derived cell lines[2]. Daratumumab (i.p. 0.5 mg/kg 14 d after challenge with Daudi-luc cells) inhibits outgrowth of CD38-expressing tumor cells in mouse xenograft tumor models[2]. Human Human IgG1 kappa Human IgG1 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Ghose J, Viola D, et al. Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. Oncoimmunology. 2018 7(10):e1486948. Published 2018 Jul 23. [Content Brief] [2]. de Weers M, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol. 2011 186(3):1840-1848. [Content Brief]
Last Update	2025-04-01 14:45:47

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