TulisokibartTulisokibart
MedChemExpress (MCE)
HY-P990007
2648504-55-4
PRA023
PRA-023
99.00%
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping with dry ice.
Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody. Tulisokibart targets to TNFSF15/TL1A. Tulisokibart can be used to study a variety of inflammatory/fibrotic diseases, such as Crohn's Disease (CD) and ulcerative colitis.
Humanized
Human IgG1 kappa
Human IgG1 kappa, Isotype Control
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[1]. Feagan B G, Sands B, Siegel C A, et al. DOP87 The Anti-TL1A Antibody PRA023 Demonstrated Proof-of-Concept in Crohn’s Disease: Phase 2a APOLLO-CD Study Results[J]. Journal of Crohn's and Colitis, 2023, 17(Supplement_1): i162-i164.
[2]. Tulisokibart. IMGT/mAb-DB.
[3]. B Sands, et al. OP40 PRA023 Demonstrated Efficacy and Favorable Safety as Induction Therapy for Moderately to Severely Active UC: Phase 2 ARTEMIS-UC Study Results, Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i56–i59