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| Supplier Name | MedChemExpress (MCE) |
| Contact | sales |
| Tel | 609-228-6898 |
| Mobile | 609-228-6898 |
| sales@medchemexpress.com; tech@medchemexpress.com | |
| Website | https://www.medchemexpress.com/ |
| Product Name | Dargistotug |
| Synonyms | Dargistotug |
| CAS | 2649362-29-6 |
| EINECS | |
| Chemical Formula | |
| Molecular Weight | |
| inchi | |
| Package | 1 mg;5 mg |
| Price | Email to quote |
| Descriptions | Dargistotug MedChemExpress (MCE) HY-P990031 M-6223 99.36% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Dargistotug (M-6223) is a fully human IgG1 monoclonal antibody targeting TIGIT (T cell immune receptor with Ig domain and ITIM). TIGIT is an inhibitory immune checkpoint that promotes NK cell depletion and reduces the secretion of cytokines by binding to CD155 and other antibodies. It can also directly or indirectly inhibit effector T cells and upregulate Tregs cells, thereby exerting immunosuppression. Function. Human Human IgG1 kappa Human IgG1 kappa, Isotype Control [1]. Harjunpää H, Guillerey C. TIGIT as an emerging immune checkpoint. Clin Exp Immunol. 2020 May |
| Last Update | 2025-04-01 14:45:47 |
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