Request for quotation
Supplier Contact
 | |
| Supplier Name | MedChemExpress (MCE) |
| Contact | sales |
| Tel | 609-228-6898 |
| Mobile | 609-228-6898 |
| sales@medchemexpress.com; tech@medchemexpress.com | |
| Website | https://www.medchemexpress.com/ |
| Product Name | Research Grade Ulviprubart (DHK27701) |
| Synonyms | Research Grade Ulviprubart (DHK27701) |
| CAS | 2569434-60-0 |
| EINECS | |
| Chemical Formula | |
| Molecular Weight | |
| inchi | |
| Package | 1 mg;5 mg |
| Price | Email to quote |
| Descriptions | Ulviprubart MedChemExpress (MCE) HY-P990026 ABC-008 96.20% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Ulviprubart (ABC-008) is a monoclonal antibody targeting the KLRG1 receptor that selectively depletes highly differentiated cytotoxic T cells. Ulviprubart can be used in the study of inclusion body myositis (IBM). Ulviprubart (10 µg/mL, 2-8 h) targets Killer cell lectin-like receptor G1 (KLRG1), eliminates self-reactive T cells through the ADCC mechanism mediated by natural killer (NK) cells[2]. Humanized Human IgG1 kappa Human IgG1 kappa, Isotype Control [1]. Brady S, et al. Inclusion body myositis: Correcting mitochondfrial and lysosomal autophagy impairment as a potential therapeutic strategy[J]. Autoimmunity Reviews, 2024: 103644. [Content Brief] [2]. Konry T, et al., Single Cell Droplet-Based Efficacy and Transcriptomic Analysis of a Novel Anti-KLRG1 Antibody for Elimination of Autoreactive T Cells. Res Sq [Preprint]. 2024 Sep 8:rs.3.rs-4745216. [Content Brief] |
| Last Update | 2025-04-01 14:45:47 |
MedChemExpress (MCE) also provides
Category: Inhibitory Antibodies
CAS: 1471999-69-5
Last Update: 2025-04-01 14:45:47
CAS: 1471999-69-5
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 565451-13-0
Last Update: 2025-04-01 14:45:47
CAS: 565451-13-0
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 1690318-25-2
Last Update: 2025-04-01 14:45:47
CAS: 1690318-25-2
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 1418200-58-4
Last Update: 2025-04-01 14:45:47
CAS: 1418200-58-4
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 2517935-02-1
Last Update: 2025-04-01 14:45:47
CAS: 2517935-02-1
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 2460539-61-9
Last Update: 2025-04-01 14:45:47
CAS: 2460539-61-9
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 2556646-63-8
Last Update: 2025-04-01 14:45:47
CAS: 2556646-63-8
Last Update: 2025-04-01 14:45:47
Category: Inhibitory Antibodies
CAS: 2490556-50-6
Last Update: 2025-04-01 14:45:47
CAS: 2490556-50-6
Last Update: 2025-04-01 14:45:47