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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product Name5-hydroxymethylcytosine
Synonyms5-hydroxymethylcytosine
5-Hydroxymethylcytosinefreebase
4-AMINO-5-(HYDROXYMETHYL)PYRIMIDIN-2-OL
4-Amino-5-(hydroxymethyl)pyrimidin-2-ol
5-(Hydroxymethyl)Cytosine Hydrochloride
4-Amino-5-hydroxymethyl-2(1H)-pyrimidinone

Synonyms

5-hydroxymethylcytosine
5-Hydroxymethylcytosinefreebase
4-AMINO-5-(HYDROXYMETHYL)PYRIMIDIN-2-OL
4-Amino-5-(hydroxymethyl)pyrimidin-2-ol
5-(Hydroxymethyl)Cytosine Hydrochloride
4-Amino-5-hydroxymethyl-2(1H)-pyrimidinone
4-AMINO-2-HYDROXY-5-HYDROXYMETHYLPYRIMIDINE
6-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one
4-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone
4-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one
2-hydroxy-4-amino-5-(hydroxymethyl)pyrimidine
2(1H)-Pyrimidinone, 4-amino-5-(hydroxymethyl)- (9CI)
CAS1123-95-1
EINECS
Chemical FormulaC5H7N3O2
Molecular Weight141.13
inchiInChI=1/C5H7N3O2/c6-4-3(2-9)1-7-5(10)8-4/h1,9H,2H2,(H3,6,7,8,10)
Package1 mg;5 mg;10 mg;25 mg;50 mg
PriceEmail to quote
Descriptions5-Hydroxymethylcytosine

5-Hydroxymethylcytosine

MedChemExpress (MCE)

HY-W018324

1123-95-1

5hmC

98.14%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US

Descriptions

5-Hydroxymethylcytosine

5-Hydroxymethylcytosine

MedChemExpress (MCE)

HY-W018324

1123-95-1

5hmC

98.14%

Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Room temperature in continental US
may vary elsewhere.

5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development.

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[1]. Gerd P Pfeifer, et al. 5-hydroxymethylcytosine and its potential roles in development and cancer. Epigenetics Chromatin. 2013 May 1
6(1):10.
[Content Brief]

[2]. Xiao-Long Cui, et al. A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 Dec 2
11(1):6161.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/5-hydroxymethylcytosine.html
Last Update2025-05-21 16:50:25
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