5-Hydroxymethylcytosine MedChemExpress (MCE)

Product Name	5-hydroxymethylcytosine
Synonyms	5-hydroxymethylcytosine 5-Hydroxymethylcytosinefreebase 4-AMINO-5-(HYDROXYMETHYL)PYRIMIDIN-2-OL 4-Amino-5-(hydroxymethyl)pyrimidin-2-ol 5-(Hydroxymethyl)Cytosine Hydrochloride 4-Amino-5-hydroxymethyl-2(1H)-pyrimidinone Synonyms 5-hydroxymethylcytosine 5-Hydroxymethylcytosinefreebase 4-AMINO-5-(HYDROXYMETHYL)PYRIMIDIN-2-OL 4-Amino-5-(hydroxymethyl)pyrimidin-2-ol 5-(Hydroxymethyl)Cytosine Hydrochloride 4-Amino-5-hydroxymethyl-2(1H)-pyrimidinone 4-AMINO-2-HYDROXY-5-HYDROXYMETHYLPYRIMIDINE 6-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one 4-Amino-5-(hydroxymethyl)-2(1H)-pyrimidinone 4-amino-5-(hydroxymethyl)pyrimidin-2(1H)-one 2-hydroxy-4-amino-5-(hydroxymethyl)pyrimidine 2(1H)-Pyrimidinone, 4-amino-5-(hydroxymethyl)- (9CI)
CAS	1123-95-1
EINECS
Chemical Formula	C5H7N3O2
Molecular Weight	141.13
inchi	InChI=1/C5H7N3O2/c6-4-3(2-9)1-7-5(10)8-4/h1,9H,2H2,(H3,6,7,8,10)
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	5-Hydroxymethylcytosine 5-Hydroxymethylcytosine MedChemExpress (MCE) HY-W018324 1123-95-1 5hmC 98.14% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions 5-Hydroxymethylcytosine 5-Hydroxymethylcytosine MedChemExpress (MCE) HY-W018324 1123-95-1 5hmC 98.14% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. 5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development. \| \| \| \| \| \| \| \| \| \| [1]. Gerd P Pfeifer, et al. 5-hydroxymethylcytosine and its potential roles in development and cancer. Epigenetics Chromatin. 2013 May 1 6(1):10. [Content Brief] [2]. Xiao-Long Cui, et al. A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 Dec 2 11(1):6161. [Content Brief]
Last Update	2025-04-01 14:45:47

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