NADP (Standard) MedChemExpress (MCE)

Product Name	beta-nicotinamide adenine dinucleotide phosphoric acid
Synonyms	TPN NADP TPNH coenzyme II nadide phosphate TRIPHOSPHOPYRIDINE NUCLEOTIDE triphosphopyridine nucleotide Synonyms TPN NADP TPNH coenzyme II nadide phosphate TRIPHOSPHOPYRIDINE NUCLEOTIDE triphosphopyridine nucleotide Nicotinamide-adenine dinucleotide phosphate B-NICOTINAMIDEADENINEDINUCLEOTIDEPHOSPHATE,HYDRATE B-NICOTINAMIDE ADENINE DINUCLEOTIDE*PHOS PHATE FREE β-nicotinamide adenine dinucleotide phosphate hydrate beta-nicotinamide adenine dinucleotide phosphoric acid [(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[[(2R,3S,4R,5R)-5-(5-carbamoylpyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-oxolan-3-yl]oxyphosphonic acid [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphate [(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] hydrogen phosphate
CAS	53-59-8
EINECS	200-178-1
Chemical Formula	C21H28N7O17P3
Molecular Weight	743.41
inchi	InChI=1/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
Package	5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	NADP (Standard) NADP (Standard) MedChemExpress (MCE) HY-113325R 53-59-8 98% Please store the product under the recommended conditions in the Certificate of Analysis. NADP (Standard) is the analytical standard of NADP. This product is intended for research and analytical applications. NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes. In Vitro:NADP can impair folate metabolism and nucleotide biosynthesis in HCT116 cells at high concentrations, leading to the cessation of proliferation and prioritizing cell survival. NADP forms NAADP through IL-8-driven CD38 to mobilize Ca2+ and influence cell migration. NADP de novo synthesis mediated by NADK upregulation provides power for anabolic reaction and antioxidant system to promote breast cancer metastasis. NADP is upregulated in ROS generation mediated by hyperglycemia and IDPc induction, thereby protecting renal cells from oxidative stress. \| \| \| \| \| \| \| \| \| \|
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Last Update	2025-05-21 16:50:25

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