Oxamic acid MedChemExpress (MCE)

Product Name	Oxamic acid
Synonyms	Oxamic acid;amino(oxo)acetate;AMINOOXOACETIC ACID;amino(oxo)acetic acid;Acetic acid, aminooxo-;2-aMino-2-oxoacetic acid;Oxamic acid Oxalic acid monoamide;Aminooxoacetic acid, Oxalic acid monoamide
CAS	471-47-6
EINECS	207-443-0
Chemical Formula	C2H3NO3
Molecular Weight	89.05
inchi	InChI=1/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)/p-1
Package	100 mg;500 mg
Price	Email to quote
Descriptions	Oxamic acid Oxamic acid MedChemExpress (MCE) HY-W013032 471-47-6 Oxamidic acid 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Oxamic acid Oxamic acid MedChemExpress (MCE) HY-W013032 471-47-6 Oxamidic acid 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Oxamic acid is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis. Oxamic acid suppresses the proliferation, migration and invasion of both A2780 and SKOV3 cells[1]. Oxamic acid (10 μM 24-72 h) inhibits cell proliferation in a dose- and time-dependent manner in both NPC cancer cells[2]. Oxamic acid (0-100 mM 24 h) induces cell cycle arrest in the G2/M phase in CNE-1 and CNE-2 cells[2]. Oxamic acid (0-100 mM 48 h) induces apoptosis via caspase-3 activation and the mitochondrial pathway in NPC cells[2]. Oxamic acid (0-100 mM 24 h) increases ROS levels in NPC cells[2]. Oxamic acid (intraperitoneal injection 750 mg/kg once daily 3 w) treatment improves the efficacy of tumor inhibition in vivo when combined with irradiation treatment[2]. \| \| \| \| \| \| \| \| \| \| [1]. Xiang J, et al. LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells. Aging (Albany NY). 2021 Dec 16 13(24):25920-25930. [Content Brief] [2]. Zhai X, et al. Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells. Oncol Rep. 2013 Dec 30(6):2983-91. [Content Brief] [3]. Muramatsu H, et al. Targeting lactate dehydrogenase‑A promotes docetaxel‑induced cytotoxicity predominantly in castration‑resistant prostate cancer cells. Oncol Rep. 2019 Jul 42(1):224-230. [Content Brief]
Supplier Website	https://www.medchemexpress.com/oxamic-acid.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-05-21 16:50:25

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-05-21 16:50:25

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-05-21 16:50:25

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-05-21 16:50:25

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-05-21 16:50:25

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-05-21 16:50:25

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-05-21 16:50:25

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact