Pulsatilla saponin D MedChemExpress (MCE)

Product Name	Pulsatillasaponin D
Synonyms	Pulsatillasaponin D Pulsatilla saponin D, BR Pulsatilla saponin D (SB365) Pulsatilla saponin D 68027-15-6 Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside Synonyms Pulsatillasaponin D Pulsatilla saponin D, BR Pulsatilla saponin D (SB365) Pulsatilla saponin D 68027-15-6 Hederagenin 3-O-α-L-rhaMnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside Hederagenin 3-O-α-L-rhamnopyranosyl(1→2)-(β-D-glucopyranosyl(1→4))-α-L-arabinopyranoside Olean-12-en-28-oic acid,3-[[O-6-deoxy-a-L-mannopyranosyl-(12)-O-[b-D-glucopyranosyl-(14)]-a-L-arabinopyranosyl]oxy]-23-hydroxy-, (3b,4a)- Olean-12-en-28-oic acid, 3-[[O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl]oxy]-23-hydroxy-, (3β,4α)-
CAS	68027-15-6
EINECS	211-708-6
Chemical Formula	C47H76O17
Molecular Weight	913.09614
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Package	10 mM * 1 mL;1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Pulsatilla saponin D Pulsatilla saponin D MedChemExpress (MCE) HY-N0834 68027-15-6 SB365 Descriptions Pulsatilla saponin D Pulsatilla saponin D MedChemExpress (MCE) HY-N0834 68027-15-6 SB365 Hederacolchiside A 98.60% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent. Pulsatilla saponin D (SB365) shows apoptotic effect accompanied by increased evidence of cleaved caspase-3 and poly (ADP ribose) polymerase[1]. Pulsatilla saponin D (SB365) strongly inhibits c-Met expression in gastric cancer cells[1]. Pulsatilla saponin D (SB365) strongly suppresses the growth and proliferation of 5 human pancreatic cancer cell lines (MIAPaCa-2, BXPC-3, PANC-1, AsPC-1 and HPAC) [2]. Pulsatilla saponin D (SB365) shows anti-angiogenic activity by decreasing the expression of HIF-1α and VEGF[3]. Pulsatilla saponin D (0.3 ng/mL to 10 μg/mL) exhibits anti-tumor activity in NSCLC cancer cells[4]. Pulsatilla saponin D (6.4 mg/kg) exhibits anti-tumor activity in Lewis lung carcinoma model[4]. \| \| \| \| \| \| \| \| \| \| [1]. Hong SW, et al. SB365, Pulsatilla saponin D, targets c-Met and exerts antiangiogenic and antitumor activities. Carcinogenesis. 2013 Sep 34(9):2156-69. [Content Brief]* [2]. Son MK, et al. SB365, Pulsatilla saponin D suppresses proliferation and induces apoptosis of pancreatic cancer cells. Oncol Rep. 2013 Aug 30(2):801-8. [Content Brief] [3]. Son MK, et al. SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway. Food Chem. 2013 Jan 1 136(1):26-33. [Content Brief] [4]. Yong Kim, et al. Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana. Arch Pharm Res. 2004 Sep 27(9):915-8. [Content Brief]
Supplier Website	https://www.medchemexpress.com/pulsatilla-saponin-d.html
Last Update	2025-05-21 16:50:25

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