Glycitein MedChemExpress (MCE)

Product Name	Glycitein
Synonyms	Glycitein Glicetein GLYCITEIN GLYCETEIN Glycetein 4,7-DIHYDROXY-6-METHOXYISOFLAVONE 7,4'-DIHYDROXY-6-METHOXYISOFLAVONE Synonyms Glycitein Glicetein GLYCITEIN GLYCETEIN Glycetein 4,7-DIHYDROXY-6-METHOXYISOFLAVONE 7,4'-DIHYDROXY-6-METHOXYISOFLAVONE 4',7-DIHYDROXY-6-METHOXYISOFLAVONE 4',7-Dihydroxy-6-methoxyisoflavone 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-
CAS	40957-83-3
EINECS
Chemical Formula	C16H12O5
Molecular Weight	284.26
inchi	InChI=1/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Glycitein Glycitein MedChemExpress (MCE) HY-N0016 40957-83-3 Glycetein 99.67% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Glycitein Glycitein MedChemExpress (MCE) HY-N0016 40957-83-3 Glycetein 99.67% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Glycitein is a soy isoflavone used to study apoptosis and antioxidant. Glycitein (0-30 μM, 4 days/20 h) inhibits the dextran-coated charcoal/fetal bovine serum (DDC-FBS)-induced growth (4 days) and DNA synthesis (20 h) of aortic smooth muscle cells (SMC) from stroke-prone spontaneously hypertensive rats (SHRSP)[3]. Glycitein (0-100 μM, 24 h) inhibits the viability in human gastric cancer cells, induces apoptosis and induces G0/G1 phase arrest[4]. Glycitein (100 μg/mL, 2 days) protects against Aβ-induced toxicity and oxidative stress in transgenic C. elegans[6]. Glycitein (3 mg/day, oral gavage, 4 days) has weak estrogenic activity, and increases uterine weight in weaning female B6D2F1 mice[1]. Glycitein (15, 30, or 45 mg/kg in diet) in sows during late pregnancy and lactation enhances antioxidative indices, decreases the content of MDA in sow's plasma and milk, improves milk composition, and enhancesthe growth performance of the sucking piglets[5]. \| \| \| \| \| \| \| \| \| \| [1]. Song TT, et al. Estrogenic activity of glycitein, a soy isoflavone. J Agric Food Chem. 1999 Apr 47(4):1607-10. [Content Brief] [2]. Yoshida H, et al. Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells. Biosci Biotechnol Biochem. 2001 May 65(5):1211-3. [Content Brief] [3]. Pan W, et al. Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke-prone spontaneously hypertensive rats. J Nutr. 2001 Apr 131(4):1154-8. [Content Brief] [4]. Zang YQ, et al. Glycitein induces reactive oxygen species-dependent apoptosis and G0/G1 cell cycle arrest through the MAPK/STAT3/NF-κB pathway in human gastric cancer cells. Drug Dev Res. 2019 Aug 80(5):573-584. [Content Brief] [5]. Hu YJ, et al. Effect of dietary supplementation with glycitein during late pregnancy and lactation on antioxidative indices and performance of primiparous sows. J Anim Sci. 2015 May 93(5):2246-54. [Content Brief] [6]. Gutierrez-Zepeda A, et al. Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans. BMC Neurosci. 2005 Aug 25 6:54. [Content Brief]
Last Update	2025-04-01 14:45:47

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