Levobupivacaine hydrochloride MedChemExpress (MCE)

Product Name	(S)-(-)-Bupivacaine Hydrochloride
Synonyms	TIMTEC-BB SBB001337 (s)-bupivacaine hcl levobupivacaine hcl Timtec-bb sbb001337 (S)-(-)-BUPIVACAINE HCL (s)-(-)-bupivacaine hcl levobupivacaine hydrochloride Synonyms TIMTEC-BB SBB001337 (s)-bupivacaine hcl levobupivacaine hcl Timtec-bb sbb001337 (S)-(-)-BUPIVACAINE HCL (s)-(-)-bupivacaine hcl levobupivacaine hydrochloride (S)-(-)-Bupivacaine Hydrochloride (S)-(-)-BUPIVACAINE HYDROCHLORIDE bupivacaine hydrochloride, monohydrate s-(-)-1-butyl-2,6-pipecoloxylidide hydrochloride s-(-)-1-butyl-2',6'-pipecoloxylidide hydrochloride (s)-1-butyl-2',6'-piperidinecarboxamidemonohydrochloride (s)-1-butyl-2',6'-piperidinecarboxamidemonohydrochloride (S)-(-)-1-BUTYL-2-(2,6-XYLYLCARBAMOYL)-PIPERIDINE HYDROCHLORIDE (s)-(-)-1-butyl-2-(2,6-xylylcarbamoyl)-piperidine hydrochloride 1-butyl-n-[2,6-dimethylphenyl]-2-piperidinecarboxamide hydrochloride (s)-(-)-1-n-butyl-2',6'-dimethyl-2-piperidincarboxanilid hydrochloride (S)-(-)-1-N-BUTYL-2',6'-DIMETHYL-2-PIPERIDINCARBOXANILID HYDROCHLORIDE 6'-pipecoloxylidide,1-butyl-,hydrochloride,(-)-2 bupicainehydrochloride(-) (s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride
CAS	27262-48-2
EINECS	1308068-626-2
Chemical Formula	C18H29ClN2O
Molecular Weight	324.89
inchi	InChI=1/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H/t16-;/m0./s1
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg;200 mg;500 mg
Price	Email to quote
Descriptions	Levobupivacaine hydrochloride Levobupivacaine hydrochloride MedChemExpress (MCE) HY-B0653A 27262-48-2 (S)-(-)-Bupivacaine monohydrochloride 99.98% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Levobupivacaine hydrochloride Levobupivacaine hydrochloride MedChemExpress (MCE) HY-B0653A 27262-48-2 (S)-(-)-Bupivacaine monohydrochloride 99.98% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local agent that can suppress or relieve pain. Levobupivacaine hydrochloride exerts agent that can suppress or relieve pain. and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer. Levobupivacaine (0-4 mM 24 h) does not affect the viability of GES-1 cells but inhibits the viability of HGC27 and SGC7901 cells[2]. Levobupivacaine (2 mM 24, 48 or 72 h) enhances Erastin-induced inhibitory impact on HGC27 and SGC7901 cell viabilities induces the levels of Fe2+, iron, and lipid ROS[2]. Levobupivacaine (2 mM 24 h) enhances the expression of miR-489-3p in HGC27 and SGC7901 cells, increases the levels of Fe2+ and iron[2]. Levobupivacaine (40 μmol/kg IP once daily for 25 days) significantly inhibits SGC7901 cell growth, and enhances the lipid ROS accumulation[2]. Levobupivacaine (5 or 36 mg/kg IP single dosage) increases the latency to partial seizures and prevents the occurrence of generalized seizures at low dosage reduces the latency to N-methyl-d-aspartate (NMDA)-induced seizures and increased seizure severity at high dosage[3]. Sodium channels, Ferroptosis[1] Cellular Effect Cell Line Type Value Description References \| \| \| \| \| \| \| \| \| \| [1]. Sanford M, et al. Levobupivacaine: a review of its use in regional anaesthesia and pain management. Drugs. 2010 Apr 16 70(6):761-91. [Content Brief] [2]. Mao SH, et al. Levobupivacaine Induces Ferroptosis by miR-489-3p/SLC7A11 Signaling in Gastric Cancer. Front Pharmacol. 2021 Jun 9 12:681338. [Content Brief] [3]. Marganella C, et al. Comparative effects of levobupivacaine and racemic bupivacaine on excitotoxic neuronal death in culture and N-methyl-D-aspartate-induced seizures in mice. Eur J Pharmacol. 2005 Aug 22 518(2-3):111-5. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-04-01 14:45:47

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-04-01 14:45:47

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-04-01 14:45:47

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-04-01 14:45:47

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-04-01 14:45:47

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-04-01 14:45:47

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-04-01 14:45:47

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact