Ascorbyl palmitate MedChemExpress (MCE)

Product Name	6-O-palmitoyl-L-ascorbic acid
Synonyms	Ascorbylpalmitate Ascorbyl Palmitate Palmitoyl ascorbate Vitamin C Palmitate L-Ascorbyl 6-Palmitate 6-O-Palmitoyl ascorbate Ascorbyl Palmitate (2 g) Synonyms Ascorbylpalmitate Ascorbyl Palmitate Palmitoyl ascorbate Vitamin C Palmitate L-Ascorbyl 6-Palmitate 6-O-Palmitoyl ascorbate Ascorbyl Palmitate (2 g) PALMITOYL L-ASCORBIC ACID L-Ascorbic acid 6-palmitate L-Ascorbic acid-6-phlmitate Ascorbyl Palmitate (2 g) (AS) 6-O-palmitoyl-L-ascorbic acid 6-O-hexadecanoylhex-1-enofuranos-3-ulose ASCORBYL PALMITATE(ASCORBIC ACID-6-PALMITATE)(P) 6-O-hexadecanoyl-L-threo-hex-1-enofuranos-3-ulose
CAS	137-66-6
EINECS	205-305-4
Chemical Formula	C22H38O7
Molecular Weight	414.53
inchi	InChI=1/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,26-27H,2-16H2,1H3/t17-,21+/m0/s1
Package	10 mM * 1 mL;10 mM * 1 mL;100 mg;100 mg;200 mg;200 mg;500 mg;500 mg
Price	Email to quote
Descriptions	Ascorbyl palmitate Ascorbyl palmitate MedChemExpress (MCE) HY-B0987 137-66-6 L-Ascorbic acid 6-hexadecanoate Descriptions Ascorbyl palmitate Ascorbyl palmitate MedChemExpress (MCE) HY-B0987 137-66-6 L-Ascorbic acid 6-hexadecanoate 6-O-Palmitoyl-L-ascorbic acid 99.61% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Ascorbyl palmitate is an orally active ester formed from ascorbic acid and palmitic acid, used as an antioxidant and food additive. Ascorbyl palmitate in preventing fat and oil oxidation is more efficient than Butylated hydroxyanisole (HY-B1066) and Butylated hydroxytoluene (HY-Y0172). Ascorbyl palmitate mitigates inhibition of collagen synthesis by select calcium and sodium channel blockers. Ascorbyl palmitate induces Apoptosis in human umbilical vein endothelial cells (HUVECs). Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome. Ascorbyl palmitate (25-400 μM, 24 h and 48 h) induces cell cytotoxicity and inhibits cell growth in HUVECs in a dose- and time-dependent manner[1]. Ascorbyl palmitate (125 μM, 24 h and 48 h) inhibits proliferation of HUVECs and induces cell death by inducing apoptosis, which decreases Bcl-2 gene expression ratio and increases Caspase-3, 9 activities in HUVECs[1]. Ascorbyl palmitate (1.25-20 μM, 72 h) dependent extracellular matrix (ECM) deposition of collagen type l is significantly reduced in aortic smooth muscle cells, which is inhibited by Nifedipine (HY-B0284) (50 µM, 72 h)[2]. Ascorbyl palmitate (0-20 μM, 1 h) has stronger inhibitory activity against NLRP3 inflammasome through its antioxidant ability than ascorbic acid in LPS (HY-D1056)-primed bone marrow-derived macrophages (BMDMs)[3]. Ascorbyl palmitate (25 mg/kg, i.p., every 2 days for 10 or 14 days) alleviates LPS (HY-D1056)-induced NLRP3 inflammasome activation, dextran sulfate sodium (DSS) (HY-116282C)-induced colitis and experimental autoimmune encephalomyelitis (EAE) in mice[3]. \| \| \| \| \| \| \| \| \| \| [1]. Sohrabi Y, et al. Cytotoxicity and Genotoxicity Assessment of Ascorbyl Palmitate (AP) Food Additive[J]. Adv Pharm Bull. 2018 Jun 8(2):341-346. [Content Brief] [2]. Ivanov V, et al. Inhibition of collagen synthesis by select calcium and sodium channel blockers can be mitigated by ascorbic acid and ascorbyl palmitate. Am J Cardiovasc Dis. 2016 May 18 6(2):26-35. [Content Brief] [3]. Zhang L, et al. Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome[J]. Int Immunopharmacol. 2024 Apr 20 131:111915. [Content Brief] [4]. Jonker D, et al. Comparison of the effects of ascorbyl palmitate and L-ascorbic acid on paracetamol-induced hepatotoxicity in the mouse[J]. Toxicology. 1988 Nov 30 52(3):287-95. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Ascorbyl-palmitate.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-05-21 16:50:25

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-05-21 16:50:25

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-05-21 16:50:25

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-05-21 16:50:25

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-05-21 16:50:25

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-05-21 16:50:25

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-05-21 16:50:25

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact