Maytansinol MedChemExpress (MCE)

Product Name	Maytansine, O3-de2-(acetylmethylamino)-1-oxopropyl-
Synonyms	MAYTANSINOL Maytansinol Maytansinoid ansaMitocin p 0 antibiotic c 15003p Maytansine,3-O-de[2- Maytansine, O3-de2-(acetylmethylamino)-1-oxopropyl- Synonyms MAYTANSINOL Maytansinol Maytansinoid ansaMitocin p 0 antibiotic c 15003p Maytansine,3-O-de[2- Maytansine, O3-de2-(acetylmethylamino)-1-oxopropyl- 3-o-de(2-(acetylMethylaMino)-1-oxopropyl)Maytansine 3-O-De[2-[methyl(acetyl)amino]-1-oxopropyl]maytansine
CAS	57103-68-1
EINECS
Chemical Formula	C28H37ClN2O8
Molecular Weight	565.05
inchi
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Maytansinol Maytansinol MedChemExpress (MCE) HY-19474 57103-68-1 Ansamitocin P-0 99.84% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Maytansinol Maytansinol MedChemExpress (MCE) HY-19474 57103-68-1 Ansamitocin P-0 99.84% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Maytansinol (Ansamitocin P-0) is a derivative of Maytansine. Maytansinol can inhibit tubulin polymerization and induce apoptosis. Maytansinol has antitumor activity. Maytansinol can be used in cancer drug research. Maytansinol (0.09-0.75 nM, 24 h) decreases the growth and survival of HCT116 cells in a dose-dependent manner [2]. Maytansinol (2 μM, 10 μM, add to food, 1-2 h) can depolymerize microtubules in Drosophila. Maytansinol (0.5-2 μM, add to food, 10 days) decreases the survival rate of wild-type and p53 mutant larvae. Maytansinol (1 or 2 μM, add to food, 24-26 h) can induce apoptosis of wild-type Drosophila cells[2]. \| \| \| \| \| \| \| \| \| \| [1]. Zafar S, et al. New insights into the anticancer therapeutic potential of maytansine and its derivatives. Biomed Pharmacother. 2023 Sep 165:115039. [Content Brief] [2]. Edwards A, et al. Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells. Dis Model Mech. 2011 Jul 4(4):496-503. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Maytansinol.html
Last Update	2025-05-21 16:50:25

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