alpha-Cyperone MedChemExpress (MCE)

Product Name	alpha-Cyperone
Synonyms	α-cyperon A-CYPERONE α-cyperone alpha-Cyperone α-Cyperone 473-08-5 alpha-Cyperone (α-Cyperone) (4aS,7R)-1,4a-Dimethyl-7-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one Synonyms α-cyperon A-CYPERONE α-cyperone alpha-Cyperone α-Cyperone 473-08-5 alpha-Cyperone (α-Cyperone) (4aS,7R)-1,4a-Dimethyl-7-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one (4aS,7R)-1,4a-dimethyl-7-(1-methylethenyl)-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one (4aS-cis)-4,4a,5,6,7,8-Hexahydro-1,4a-dimethyl-7-(1-methylethenyl)-2(3H)-naphthalenone
CAS	473-08-5
EINECS
Chemical Formula	C15H22O
Molecular Weight	218.33
inchi	InChI=1/C15H22O/c1-10(2)12-5-7-15(4)8-6-14(16)11(3)13(15)9-12/h12H,1,5-9H2,2-4H3/t12-,15+/m1/s1
Package	5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	alpha-Cyperone alpha-Cyperone MedChemExpress (MCE) HY-N0710 473-08-5 α-Cyperone Descriptions alpha-Cyperone alpha-Cyperone MedChemExpress (MCE) HY-N0710 473-08-5 α-Cyperone (+)-α-Cyperone 99.80% Pure form -20°C 3 years 4°C 2 years The compound is unstable in solutions, freshly prepared is recommended. Room temperature in continental US may vary elsewhere. alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD. The anti-inflammatory activity of alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells[1]. alpha-Cyperone (α-Cyperone) binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter[2]. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Jung, S. H. et al. alpha-Cyperone, isolated from the rhizomes of Cyperus rotundus, inhibits LPS-induced COX-2 expression and PGE2 production through the negative regulation of NFkappaB signalling in RAW 264.7 cells. Journal of ethnopharmacology 147, 208-214, doi:10.1016/j.jep.2013.02.034 (2013). [Content Brief]* [2]. Azimi, A. et al. alpha-Cyperone of Cyperus rotundus is an effective candidate for reduction of inflammation by destabilization of microtubule fibers in brain. Journal of ethnopharmacology, doi:10.1016/j.jep.2016.06.058 (2016). [Content Brief]
Last Update	2025-04-01 14:45:47

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