Fucoxanthin MedChemExpress (MCE)

Product Name	Fucoxanthin
Synonyms	Fucoxanthin Fucoxanthin solution all-trans-Fucoxanthin (3S,3'S,5R,5'R,6S,6'R)- Fucoxanthin DISCONTINUED Fucoxanthin, froM LaMinariajaponicaAresch 6'R,7'-didehydro-5R,6-epoxy-4',5',6S,7-tetrahydro-3S,3'S,5'R-trihydroxy-β,β-caroten-8(5H)-one Synonyms Fucoxanthin Fucoxanthin solution all-trans-Fucoxanthin (3S,3'S,5R,5'R,6S,6'R)- Fucoxanthin DISCONTINUED Fucoxanthin, froM LaMinariajaponicaAresch 6'R,7'-didehydro-5R,6-epoxy-4',5',6S,7-tetrahydro-3S,3'S,5'R-trihydroxy-β,β-caroten-8(5H)-one (3S,3'S,5R,5'R,6S,6'R)-6',7'-Didehydro-5,6-epoxy-4',5',6,7-tetrahydro-3,3',5'-trihydroxy-,-caroten-8(5H)-one
CAS	3351-86-8
EINECS	200-486-6
Chemical Formula	C42H58O6
Molecular Weight	658.917
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Package	10 mM * 1 mL;1 mg;2 mg;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Fucoxanthin Fucoxanthin MedChemExpress (MCE) HY-N2302 3351-86-8 all-trans-Fucoxanthin 98.99% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Fucoxanthin Fucoxanthin MedChemExpress (MCE) HY-N2302 3351-86-8 all-trans-Fucoxanthin 98.99% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities. Fucoxanthin (2.8-6.2 µM, 24 h) shows obvious bacteriostatic effect on all tested Mtb strains, with MIC values of 2.8-4.1 µM[4]. Fucoxanthin (0-25 µM, 24 h) inhibits the proliferation of HeLa and SiHa cervical cancer cell lines and promotes cell stasis in the G0/G1 cell cycle phase[5]. Fucoxanthin (10 µM, 12 h) inhibits the cell viability of HTLV-1-infected T cell lines by inducing G1 cell cycle arrest and apoptosis, thereby exhibiting anticancer activity[7]. Fucoxanthin (0-100 µg/mL, 24 h) dose-dependent inhibits the expression of TNF-α, PGE2, iNOS and COX-2 proteins in RAW 264.7 cells[8]. Fucoxanthin (10-2000 mg/kg, p.o.) does not cause death or abnormal appearance in ICR mice and rats[3]. Fucoxanthin (10-50 mg/kg/day, p.o.) can protect the cadmium-induced renal injury mouse model by improving the antioxidant capacity of mice[9]. Fucoxanthin (0.1-10 mg/kg, i.v.) shows a dose-dependent anti-ocular inflammatory effect on EIU (endotoxin-induced uveitis) [8]. PPARγ UCP1 PPARα iNOS Caspase 3 Caspase-8 Caspase 9 SOD ERK2 \| \| \| \| \| \| \| \| \| \| [1]. Gammone MA, et al. Anti-obesity activity of the marine carotenoid fucoxanthin. Mar Drugs. 2015 Apr 13 13(4):2196-214. [Content Brief] [2]. Méresse S, Fodil M, Fleury F, Chénais B. Fucoxanthin, a Marine-Derived Carotenoid from Brown Seaweeds and Microalgae: A Promising Bioactive Compound for Cancer Therapy. Int J Mol Sci. 2020 21(23):9273. [Content Brief] [3]. Yoshimi Niwano, et al. In Vivo and in Vitro Toxicity Studies of Fucoxanthin, a Marine Carotenoid. null. 2011 0 (0):319-328. [4]. Šudomová M, et al. A Microbiological, Toxicological, and Biochemical Study of the Effects of Fucoxanthin, a Marine Carotenoid, on Mycobacterium tuberculosis and the Enzymes Implicated in Its Cell Wall: A Link Between Mycobacterial Infection and Autoimmune Diseases. Mar Drugs. 2019 Nov 14 17(11):641. [Content Brief] [5]. Ye G, et al. Fucoxanthin may inhibit cervical cancer cell proliferation via downregulation of HIST1H3D. J Int Med Res. 2020 Oct 48(10):300060520964011. [Content Brief] [6]. Okuzumi J, et al. Inhibitory effects of fucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumor cells. Cancer Lett. 1990 Nov 19 55(1):75-81. [Content Brief] [7]. Ishikawa C, et al. Anti-adult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol. Int J Cancer. 2008 Dec 1 123(11):2702-12. [Content Brief] [8]. Shiratori K, et al. Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Exp Eye Res. 2005 Oct 81(4):422-8. [Content Brief] [9]. Yang H, et al. Role of Fucoxanthin towards Cadmium-induced renal impairment with the antioxidant and anti-lipid peroxide activities. Bioengineered. 2021 Dec 12(1):7235-7247. [Content Brief]
Last Update	2025-04-01 14:45:47

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