Desaminotyrosine MedChemExpress (MCE)

Product Name	P-Hydroxybenzene propanoic acid
Synonyms	Phloretate Phloretic acid PHLORETIC ACID DESAMINOTYROSINE PHLORETINIC ACID 4-hydroxybenzenepropanoic 4-Hydroxyhydrocinnamic acid Synonyms Phloretate Phloretic acid PHLORETIC ACID DESAMINOTYROSINE PHLORETINIC ACID 4-hydroxybenzenepropanoic 4-Hydroxyhydrocinnamic acid 4-hydroxyphenylpropionicacid 4-hydroxybenzenepropanoicacid 4-Hydroxyphenylpropionic acid 3-(4-hydroxyphenyl)propanoate 4-hydroxy-benzenepropanoicaci 4-Hydroxybenzenepropanoic acid p-Hydroxyphenylpropionic acid p-Hydroxyphenyl-propionic acid P-Hydroxybenzene propanoic acid 2-(4-hydroxyphenyl)propanoic acid 3-(4-Hydroxyphenyl)propionic acid Benzenepropanoic acid, 4-hydroxy- 3-(4-hydroxyphenyl)propanoic acid 3-(para-Hydroxyphenyl)-propionic acid
CAS	501-97-3
EINECS	207-931-3
Chemical Formula	C9H10O3
Molecular Weight	166.17
inchi	InChI=1/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12)/p-1
Package	10 mM * 1 mL;10 mM * 1 mL;100 mg;100 mg
Price	Email to quote
Descriptions	Desaminotyrosine Desaminotyrosine MedChemExpress (MCE) HY-W015346 501-97-3 3-(4-Hydroxyphenyl)propionic acid 99.80% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Desaminotyrosine Desaminotyrosine MedChemExpress (MCE) HY-W015346 501-97-3 3-(4-Hydroxyphenyl)propionic acid 99.80% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling. Wild-type mice produce nanomoles of Desaminotyrosine per gram of feces and have picomolar quantities of Desaminotyrosine in the serum. Desaminotyrosine (200 mM) treatment before influenza infection, protects from influenza by type I interferon (IFN) signaling, with no effect on weight loss or survival in mice with or without vancomycin, neomycin, ampicillin, and metronidazole (VNAM). Desaminotyrosine enhances type I IFN in macrophages via type I IFN amplification in mice[1]. Mice[1] Indicated mice receive 200 mM Desaminotyrosine dissolved in Kool-Aid in the drinking water (control animals receive Kool-Aid alone). Indicated mice receive poly(IC) injections of 1 mg/kg for vancomycin, neomycin, ampicillin, and metronidazole (VNAM) treated mice or 5 mg/kg for all other mice intraperitoneally daily for 4 days, and then mice are scarified on day five at which time serum is collected[1]. Microbial Metabolite Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Steed AL, et al. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science. 2017 Aug 4 357(6350):498-502. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Desaminotyrosine.html
Last Update	2025-05-21 16:50:25

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