OVA Peptide(257-264) MedChemExpress (MCE)

Product Name	Ovalbumin (257-264) chicken
Synonyms	SIINFEKL OVA (257-264) OVA PEPTIDE (257-264) OVA (257-264) (CHICKEN) Ovalbumin (257-264) chicken SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU OVALBUMIN(257-264) ANTIGEN PEPTIDE Synonyms SIINFEKL OVA (257-264) OVA PEPTIDE (257-264) OVA (257-264) (CHICKEN) Ovalbumin (257-264) chicken SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU OVALBUMIN(257-264) ANTIGEN PEPTIDE OVALBUMIN FRAGMENT - CHICKEN (257-264)
CAS	138831-86-4
EINECS
Chemical Formula	C45H74N10O13· xC2HF3O2
Molecular Weight	963.13 (free base ba
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	OVA Peptide(257-264) OVA Peptide(257-264) MedChemExpress (MCE) HY-P1489 138831-86-4 99.68% Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 year In solvent : -80°C, 6 months Descriptions OVA Peptide(257-264) OVA Peptide(257-264) MedChemExpress (MCE) HY-P1489 138831-86-4 99.68% Sealed storage, away from moisture Powder -80°C 2 years -20°C 1 year In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. OVA Peptide(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide(257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide(257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide(257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide(257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1]. TAPl-/- or C57BL/6 macrophages are co-incubated with either bacteria or polystyrene beads containing the 257-264 epitope from ovalbumin [OVA Peptide(257-264)], which binds the mouse class I molecule Kb. The source of the OVA(257-264) epitope is either the Crl-OVA(257-264) (Crl-OVA) fusion protein, the maltose binding protein (MBP)-Crl-OVA fusion protein, native OVA or bacterial recombinant OVA (rOVA) Crl-OVA, MBP-Crl-OVA and rOVA are each expressed in bacteria, and Crl-OVA and MBP-Crl-OVA purified from bacterial lysates and native egg OVA are coated onto polystyrene beads[1]. Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu \| \| \| \| \| \| \| \| \| \| [1]. Wick MJ, et al. Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur J Immunol. 1996 Nov 26(11):2790-9. [Content Brief]
Supplier Website	https://www.medchemexpress.com/OVA_Peptide_257-264.html
Last Update	2025-05-21 16:50:25

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