Ergosterol MedChemExpress (MCE)

Product Name	Ergosterol
Synonyms	Ergosterol Provitamin D2 ergosta-5,7,22-trien-3-ol (22E)-Ergosta-5,7,22-trien-3-ol (22E)-ergosta-5,7,22-trien-3-ol (3beta)-Ergosta-5,7,22- trien-3-ol (22E,24R)-Ergosta-5,7,22-trien-3-ol Synonyms Ergosterol Provitamin D2 ergosta-5,7,22-trien-3-ol (22E)-Ergosta-5,7,22-trien-3-ol (22E)-ergosta-5,7,22-trien-3-ol (3beta)-Ergosta-5,7,22- trien-3-ol (22E,24R)-Ergosta-5,7,22-trien-3-ol (22E)-Ergosta-5,7,22-trien-3beta-ol (3beta,22E)-ergosta-5,7,22-trien-3-ol Ergosterol (22E)-Ergosta-5,7,22-trien-3β-ol 7,22-trien-3-ol, (3.beta.)-Ergosta-5 delta-5,7,22-ergostatrien-3beta-ol 3β-Hydroxy-5,7,22-ergostatriene, 5,7,22-Ergostatrien-3β-ol, Provitamin D2 (3S,9S,10R,13R,17R)-10,13-dimethyl-17-[(E)-1,4,5-trimethylhex-2-enyl]-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
CAS	57-87-4
EINECS	200-352-7
Chemical Formula	C28H44O
Molecular Weight	396.66
inchi	InChI=1/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19?,20?,22-,24+,25?,26-,27-,28+/m0/s1
Package	100 mg
Price	Email to quote
Descriptions	Ergosterol Ergosterol MedChemExpress (MCE) HY-N0181 57-87-4 99.17% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Ergosterol Ergosterol MedChemExpress (MCE) HY-N0181 57-87-4 99.17% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects. Ergosterol (25, 50 mg/kg, p.o.) significantly mitigates the reduced cardiac performance in rats induced by LPS, increases SOD activity and decreases the formation of MDA, CK-MB, and LDH in LPS-induced sepsis rats[1]. Rats[2] Experimental myocardial injury in rats is performed by LPS injection (15 mg/kg). Dexmedetomidine (Dex) is used as a positive control. The experimental animals are randomly divided into five groups (n = 10) as follows: Control group, rats receive 2% gum acacia suspension orally at a dose of 2 mL/kg for 5 days, followed by normal saline injected intraperitoneally on day 5 LPS group, rats receive 2% gum acacia suspension at dose of 2 mL/kg for 5 days with LPS simultaneously injected intraperitoneally day 5 LPS+ Dex group, rats are treated with 2 mg/kg Dex suspension followed by LPS injection on day 5 LPS + Ergosterol (25 mg/kg, 50 mg/kg) groups, 25 or 50 mg/kg Ergosterol are given to rats orally for 5 consecutive days, and LPS is injected on day 5. Twelve hours after LPS treatment, blood samples are collected through the retro-orbital plexus. The serum specimens are centrifugated at 4, 000 × g for 15 min and stored at −80°C until needed. Thereafter, rats are anesthetized and sacrificed. Heart tissues are removed and homogenized in ice-cold phosphate buffered saline (50 mM, pH 7.4). Heart tissue homogenates from different groups are centrifuged at 12, 000 × g for 45 min at 4°C and the supernatants retained for further biochemical evaluations[2]. \| \| \| \| \| \| \| \| \| \| [1]. Xu J, et al. Ergosterol Attenuates LPS-Induced Myocardial Injury by Modulating Oxidative Stress and Apoptosis in Rats. Cell Physiol Biochem. 2018 48(2):583-592. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Ergosterol.html
Last Update	2025-05-21 16:50:25

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