DPPC MedChemExpress (MCE)

Product Name	L-alpha-Dipalmitoyl phosphatidylcholine
Synonyms	colfosceril palmitate L-a-Lecitin-dipalmitoyl L-a-Dipalmitoyl Lecithin L-A-LECITHIN DIPALMITOYL L-alpha-Dipalmitoyl phosphatidylcholine 1,2-dipalmitoyl-3-sn-phosphatidylcholine 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Synonyms colfosceril palmitate L-a-Lecitin-dipalmitoyl L-a-Dipalmitoyl Lecithin L-A-LECITHIN DIPALMITOYL L-alpha-Dipalmitoyl phosphatidylcholine 1,2-dipalmitoyl-3-sn-phosphatidylcholine 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine 1,2-dipalmitoyl-L-alpha-phosphatidylcholine L-A-phosphatidylcholine dipalmitoyl*synthetic 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 1,2-DIHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate (R)-2,3-Bis(palMitoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
CAS	63-89-8
EINECS	200-567-6
Chemical Formula	C40H80NO8P
Molecular Weight	734.04
inchi	InChI=1/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	DPPC DPPC MedChemExpress (MCE) HY-109506 63-89-8 129Y83 99.84% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions DPPC DPPC MedChemExpress (MCE) HY-109506 63-89-8 129Y83 99.84% -20°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice. DPPC (2-10 mg/ml) monolayer can be inserted by Aβ40, but the amount of insertion is smaller than that of DPPG or DPTAP. The behavior of Aβ40 inserted into the DPPC monolayer is affected by surface pressure, solvent (water or PBS), and salt concentration[3]. DPPC can mix with DPPE to form DPPC/DPPE lipid bilayer systems. As DPPE concentration rises, the average area per headgroup diminishes (0.65 to 0.52 nm²), enhancing membrane compactness. Meanwhile, membrane thickness slightly increases (3.43 to 4.00 nm), reflecting lipid tail ordering. [5]. DPPC（0.5 μmol, 7 days) can serve as a critical component that enhances the stability of lipid membrane structures in liposome construction. GSL antigen was virtually non-immunogenic by itself, but GSL antigen-containing DMPC-liposome can enhance the immunogenicity of GSL antigen in mice[2]. Human Endogenous Metabolite Microbial Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov 10(6):781-811. [Content Brief] [2]. Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec 67(12):1197-201. [Content Brief] [3]. Ege C, et al. Insertion of Alzheimer's A beta 40 peptide into lipid monolayers. Biophys J. 2004 Sep 87(3):1732-40. [Content Brief] [4]. Kalra VK, et al. Transport of amino acids in gamma-glutamyl transpeptidase-implanted human erythrocytes. J Biol Chem. 1981 Jun 10 256(11):5567-71. [Content Brief] [5]. Leekumjorn S, et al. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys J. 2006 Jun 1 90(11):3951-65. [Content Brief]
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Last Update	2025-05-21 16:50:25

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