L-Ascorbic acid 2-phosphate trisodium MedChemExpress (MCE)

Product Name	Sodium L-ascorbyl-2-phosphate
Synonyms	SAP Sodium L-ascorbyl-2- L-Ascorbic-2-Phosphate Sodium Ascorbyl Phosphate Vitamin C sodium phosphate Sodium L-ascorbyl-2-phosphate L-Ascorbic acid-2-phosphate sodium Synonyms SAP Sodium L-ascorbyl-2- L-Ascorbic-2-Phosphate Sodium Ascorbyl Phosphate Vitamin C sodium phosphate Sodium L-ascorbyl-2-phosphate L-Ascorbic acid-2-phosphate sodium 2-PHOSPHO-L-ASCORBIC ACID TRISODIUM 2-Phospho-L-ascorbic acid trisodium salt L-Ascorbic acid 2-phosphate trisodium salt 2-(Dihydrogen phosphate)-L-ascorbic acid sodium salt L-Ascorbic acid 2-phosphate trisodium salt, Sodium L-ascorbyl-2-phosphate SodiuM (R)-5-((S)-1,2-dihydroxyethyl)-4-hydroxy-2-oxo-2,5-dihydrofuran-3-yl phosphate
CAS	66170-10-3
EINECS	1308068-626-2
Chemical Formula	C6H10NaO9P
Molecular Weight	280.1
inchi	InChI=1/C6H8O6.3Na.H3O4P/c7-1-2(8)5-3(9)4(10)6(11)12-5;;;;1-5(2,3)4/h2,5,7-10H,1H2;;;;(H3,1,2,3,4)/q;3*+1;/p-3/t2-,5+;;;;/m0..../s1
Package	10 mM * 1 mL;500 mg;1 g
Price	Email to quote
Descriptions	L-Ascorbic acid 2-phosphate trisodium L-Ascorbic acid 2-phosphate trisodium MedChemExpress (MCE) HY-107837 66170-10-3 2-Phospho-L-ascorbic acid trisodium 99.45% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions L-Ascorbic acid 2-phosphate trisodium L-Ascorbic acid 2-phosphate trisodium MedChemExpress (MCE) HY-107837 66170-10-3 2-Phospho-L-ascorbic acid trisodium 99.45% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-Ascorbic acid 2-phosphate (0.1-1.5 mM 2 to 3 weeks with medium exchange every 2 to 3 days) trisodium significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect [1]. L-Ascorbic acid 2-phosphate (50 μM-250 μM) trisodium is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 μM AsA2-P and 10 nM dexamethasone (Dex), and 250 μM AsA2-P and 5 nM Dex[3]. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7 52(12):8711-7. [Content Brief] [2]. Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25 266(15):9997-10003. [Content Brief] [3]. Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15 4(1):17. [Content Brief]
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Last Update	2025-05-21 16:50:25

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