3'-Methoxypuerarin MedChemExpress (MCE)

Product Name	3'- Methoxy Puerarin
Synonyms	3''-METHOXYPUERARIN Puerariaglycoside 3 Methoxypuerarin, 3'- 3'- Methoxy Puerarin 4H-1-Benzopyran-4-one,8-b-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- Synonyms 3''-METHOXYPUERARIN Puerariaglycoside 3 Methoxypuerarin, 3'- 3'- Methoxy Puerarin 4H-1-Benzopyran-4-one,8-b-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)- 8-beta-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
CAS	117047-07-1
EINECS
Chemical Formula	C22H22O10
Molecular Weight	446.4
inchi
Package	1 mg;1 mg;5 mg;5 mg;10 mg;10 mg;25 mg;25 mg;50 mg;50 mg
Price	Email to quote
Descriptions	3'-Methoxypuerarin 3'-Methoxypuerarin MedChemExpress (MCE) HY-N1978 117047-07-1 99.75% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions 3'-Methoxypuerarin 3'-Methoxypuerarin MedChemExpress (MCE) HY-N1978 117047-07-1 99.75% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. 3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radix puerariae that shows neuron protection activity. 3'-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3'-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis[1]. Rats[1] Male Wistar rats, weighing 260-320 g are randomly divided into three groups (n = 8 per group). [1] I/R+3'-MOP group: the rats undergo 8 minutes of ischemia and then 3 days of reperfusion. The 3'-Methoxypuerarin (60 mg/kg i.p.) is administrated at the moment of clamping of the carotid arteries. The rats receive daily i.p. injection of 3'-Methoxypuerarin for 3 days. [2] I/R group: the rats undergo 8 minutes of ischemia and 72 h of reperfusion. The same volume of solvent (35% polyethylene glycol solution) is administrated in the same way as 3'-Methoxypuerarin. [3] Control group: the rats undergo a sham operation. Vertebral and carotid arteries are exposed but not occluded. The rats receive a daily i.p. injection of 35% polyethylene glycol solution for 3 days[1]. \| \| \| \| \| \| \| \| \| \| [1]. Liu Y, et al. Protection by 3'-methoxypuerarin of rat hippocampal neurons against ischemia/reperfusion injury. Chin J Physiol. 2010 Apr 30 53(2):136-40. [Content Brief]
Last Update	2025-04-01 14:45:47

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