Etanercept MedChemExpress (MCE)

Product Name	TNFR-Fc fusion protein
Synonyms	Embrel;Enbrel;Etanercept;rhu-TNFR-Fc;Entanercept;TNFR-Fc fusion protein;1-235-TuMor necrosisfactor receptor (huMan) fusion protein with 236-467-iMMunoglobulin G1 (huMan g1-chain Fc fragMent) (9CI)
CAS	185243-69-0
EINECS
Chemical Formula	H4NO3V
Molecular Weight	116.97816
inchi
Package	1 mg;1 mg
Price	Email to quote
Descriptions	Etanercept Etanercept MedChemExpress (MCE) HY-108847 185243-69-0 99.20% Please store the product under the recommended conditions in the Certificate of Analysis. Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis. Etanercept (10 mg/kg Descriptions Etanercept Etanercept MedChemExpress (MCE) HY-108847 185243-69-0 99.20% Please store the product under the recommended conditions in the Certificate of Analysis. Etanercept, a dimeric fusion protein that binds TNF, acts as a TNF inhibitor. Etanercept competitively inhibits the binding of both TNF-α and TNF-β to cell surface TNF receptors, rendering TNF biologically inactive. Etanercept shows efficacy against rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis. Etanercept (10 mg/kg s.c. every 3 days for 3 weeks) significantly decreases the mean arthritis scores and radiological score[4]. Fas Human \| \| \| \| \| \| \| \| \| \| [1]. Goffe B, et al. Etanercept: An overview. J Am Acad Dermatol. 2003 49(2 Suppl):S105-S111. [Content Brief] [2]. Goldenberg MM. Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis. Clin Ther. 1999 21(1):75-2. [Content Brief] [3]. Haraoui B, et al. Etanercept in the treatment of rheumatoid arthritis. Ther Clin Risk Manag. 2007 3(1):99-105. [Content Brief] [4]. Totoson P, et al. Etanercept improves endothelial function via pleiotropic effects in rat adjuvant-induced arthritis. Rheumatology (Oxford). 2016 55(7):1308-1317. [Content Brief]
Last Update	2025-04-01 14:45:47

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