Flurbiprofen-d3 MedChemExpress (MCE)

Product Name	Flurbiprofen-d3
Synonyms	FLURBIPROFEN-D3 Flurbiprofen-d3 [2H3]-Flurbiprofen 3-Fluoro-4-phenylhydratropic Acid-d3 2-Fluoro-α-(Methyl-d3)-4-diphenylacetic Acid 2-Fluoro-α-(Methyl-d3)-[1,1'-biphenyl]-4-acetic Acid Synonyms FLURBIPROFEN-D3 Flurbiprofen-d3 [2H3]-Flurbiprofen 3-Fluoro-4-phenylhydratropic Acid-d3 2-Fluoro-α-(Methyl-d3)-4-diphenylacetic Acid 2-Fluoro-α-(Methyl-d3)-[1,1'-biphenyl]-4-acetic Acid 2-Fluoro-a-trideuteromethyl-[1,1biphenyl]-4-acetic Acid,
CAS	1185133-81-6
EINECS
Chemical Formula	C15H13FO2
Molecular Weight	244.2609232
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Flurbiprofen-d3 Flurbiprofen-d3 MedChemExpress (MCE) HY-10582S 1185133-81-6 dl-Flurbiprofen-d3 99.94% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Flurbiprofen-d3 Flurbiprofen-d3 MedChemExpress (MCE) HY-10582S 1185133-81-6 dl-Flurbiprofen-d3 99.94% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Flurbiprofen-d3 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3]. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 53(2):211-216. [Content Brief] [2]. Xiaobo Wang, et al. Flurbiprofen suppresses the inflammation, proliferation, invasion and migration of colorectal cancer cells via COX2. Oncol Lett. 2020 Nov 20(5): 132. [Content Brief] [3]. E M Glenn, et al. The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A potent non-steroidal anti-inflammatory drug. Agents Actions. 1973 Nov 3(4):210-6. [Content Brief] [4]. Hosoi, T., et al., Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress. EMBO Mol Med, 2014. [Content Brief]
Supplier Website	https://www.medchemexpress.com/flurbiprofen-d3.html
Last Update	2025-05-21 16:50:25

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