Fenbendazole-d3 MedChemExpress (MCE)

Product Name	Fenbendazole-d3
Synonyms	Fenbendazole-d3;[2H3]-Fenbendazole;Fenbendazole-d3 (methyl-d3);N-[6-(Phenylthio)-1H-benziMidazol-2-yl]carbaMic Acid Methyl-d3 Ester
CAS	1228182-47-5
EINECS
Chemical Formula	C15H13N3O2S
Molecular Weight	299.35
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Fenbendazole-d3 Fenbendazole-d3 MedChemExpress (MCE) HY-B0413S 1228182-47-5 99.46% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Fenbendazole-d3 Fenbendazole-d3 MedChemExpress (MCE) HY-B0413S 1228182-47-5 99.46% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4]. Fenbendazole-d3 (20 µM for 48 h) reverses the inhibiting influence exerted by miR-143-5p on proliferation, colony-forming capacity, and migration[1]. Fenbendazole-d3 (10 µM for 48 h) elevates the protein expression levels of HIF-1α and GLUT1[1]. \| \| \| \| \| \| \| \| \| \| [1]. Jia Xu, et al. miR-143-5p suppresses breast cancer progression by targeting the HIF-1α-related GLUT1 pathway. Oncol Lett. 2022 May 23(5):147. [Content Brief] [2]. Nilambra Dogra, et al. Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. Sci Rep. 2018 Aug 9 8(1):11926. [Content Brief] [3]. Hossein Aleyasin, et al. Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin. Antioxid Redox Signal. 2015 Jan 10 22(2):121-34. [Content Brief] [4]. Qiwen Duan, et al. Fenbendazole as a potential anticancer drug. Anticancer Res. 2013 Feb 33(2):355-62. [Content Brief]
Supplier Website	https://www.medchemexpress.com/fenbendazole-d3.html
Last Update	2025-05-21 16:50:25

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