Phloracetophenone MedChemExpress (MCE)

Product Name	2',4',6'-Trihydroxyacetophenone monohydrate
Synonyms	PHLOROACETOPHENONE 2-ACETYLPHLOROGLUCINOL 2,4,6-TRIHYDROXYACETOPHENONE 2,4,6-Trihydroxyacetophenone 2',4',6'-TRIHYDROXYACETOPHENONE 2-ACETYLPHLOROGLUCINOL MONOHYDRATE 2,4,6-TRIHYDROXYACETOPHENONE HYDRATE Synonyms PHLOROACETOPHENONE 2-ACETYLPHLOROGLUCINOL 2,4,6-TRIHYDROXYACETOPHENONE 2,4,6-Trihydroxyacetophenone 2',4',6'-TRIHYDROXYACETOPHENONE 2-ACETYLPHLOROGLUCINOL MONOHYDRATE 2,4,6-TRIHYDROXYACETOPHENONE HYDRATE 2'4'6'-TRIHYDROXYACETOPHENONE N-HYDRATE 2,4,6-trihydroxylacetophenone monohydrate 2',4',6'-TRIHYDROXYACETOPHENONE MONOHYDRATE 2',4',6'-Trihydroxyacetophenone monohydrate 1-(2,4,6-TRIHYDROXYPHENYL)ETHAN-1-ONE HYDRATE
CAS	480-66-0;249278-28-2
EINECS	640-432-2
Chemical Formula	C8H10O5
Molecular Weight	186.16
inchi	InChI=1/C8H8O4.H2O/c1-4(9)8-6(11)2-5(10)3-7(8)12;/h2-3,10-12H,1H3;1H2
Package	10 mM * 1 mL;25 g;50 g;100 g;500 g
Price	Email to quote
Descriptions	Phloracetophenone Phloracetophenone MedChemExpress (MCE) HY-W008226 480-66-0 2,4,6-trihydroxyacetophenone Descriptions Phloracetophenone Phloracetophenone MedChemExpress (MCE) HY-W008226 480-66-0 2,4,6-trihydroxyacetophenone 1-(2,4,6-Trihydroxyphenyl)ethanone 99.98% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained from Curcuma comosa Roxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) activity. Phloracetophenone stimulats bile secretion mediated through Mrp2. Phloracetophenone (2,4,6-trihydroxyacetophenone) is a cholesterol-lowering agent, enhances cholesterol 7α-hydroxylase (CYP7A1) activity, and elevates CYP7A1 mRNA level[1]. Phloracetophenone (1, 2, and 4 μmol/min) immediately and dose-dependently increases bile acid-independent bile flow in the isolated perfused rat liver[2]. Phloracetophenone (2,4,6-trihydroxyacetophenone 125 or 250 μmol/kg, intraduodenal injection) shows choleretic activity requiring multidrug resistance protein-2 (Mrp2) in rats. Phloracetophenone (40 μmol/min) partially prevents the E2-17G induced cholestasis[2]. Cholesterol 7α-hydroxylase[1], Mrp2[2] Cellular Effect Cell Line Type Value Description References \| \| \| \| \| \| \| \| \| \| [1]. Charoenteeraboon J, et al. Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. Eur J Pharmacol. 2005 May 16 515(1-3):43-6. [Content Brief] [2]. Piyachaturawat P, et al. Choleretic activity of phloracetophenone in rats: structure-function studies using acetophenone analogues. Eur J Pharmacol. 2000 Jan 10 387(2):221-7. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Phloracetophenone.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-05-21 16:50:25

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-05-21 16:50:25

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-05-21 16:50:25

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-05-21 16:50:25

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-05-21 16:50:25

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-05-21 16:50:25

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-05-21 16:50:25

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact