Nicotinamide riboside chloride MedChemExpress (MCE)

Product Name	Nicotinamide Riboside Chloride(NRC)
Synonyms	Nicotinamide Riboside.Cl Nicotimide riboside chloride Nicotinamide riboside chloride Nicotinamide Riboside Chloride(NRC) Nicotinamide B-D Riboside Chloride(WX900111) 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride Synonyms Nicotinamide Riboside.Cl Nicotimide riboside chloride Nicotinamide riboside chloride Nicotinamide Riboside Chloride(NRC) Nicotinamide B-D Riboside Chloride(WX900111) 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride 3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride
CAS	23111-00-4
EINECS	200-184-4
Chemical Formula	C11H15N2O5.Cl
Molecular Weight	290.7002
inchi
Package	10 mM * 1 mL;25 mg;50 mg;100 mg;500 mg;1 g
Price	Email to quote
Descriptions	Nicotinamide riboside chloride Nicotinamide riboside chloride MedChemExpress (MCE) HY-123033A 23111-00-4 99.90% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Nicotinamide riboside chloride Nicotinamide riboside chloride MedChemExpress (MCE) HY-123033A 23111-00-4 99.90% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease. Nicotinamide riboside Chloride (0.5 mM 24 hours) reduces the acetylation status of Ndufa9 and SOD2[1]. Nicotinamide riboside Chloride increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 μM[1]. Nicotinamide riboside chloride boosts NAD to restore antiviral poly(ADP-ribose) polymerase (PARP) functions to support innate immunity for coronavirus (CoVs), a cause of COVID-19[3]. Chronic Nicotinamide riboside Chloride (p.o. 400 mg/kg/day for 16 weeks) supplementation increases plasma and intracellular NAD+ content in a tissue-specific manner[1]. SIRT1 SIRT3 Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Cantó C, et al. The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protectsagainst high-fat diet-induced obesity. Cell Metab. 2012 Jun 6 15(6):838-47. [Content Brief] [2]. Bing Gong, et al. Nicotinamide Riboside Restores Cognition Through an Upregulation of Proliferator-Activated Receptor-γ Coactivator 1α Regulated β-Secretase 1 Degradation and Mitochondrial Gene Expression in Alzheimer's Mouse Models. Neurobiol Aging. 2013 Jun 34(6):1581-8. [Content Brief] [3]. Collin D Heer, et al. Coronavirus and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity. bioRxiv. 2020 Apr 30 2020.04.17.047480. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-04-01 14:45:47

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-04-01 14:45:47

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-04-01 14:45:47

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-04-01 14:45:47

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-04-01 14:45:47

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-04-01 14:45:47

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-04-01 14:45:47

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact