Chrysosplenetin MedChemExpress (MCE)

Product Name	Chrysosplenetin
Synonyms	EMD-20940 Chrysosplenetin chrgsosplenetin B chrysosplenetin B 3,6,7,3'-Tetramethylquercetagetin 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxychromen-4-one 4H-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy- Synonyms EMD-20940 Chrysosplenetin chrgsosplenetin B chrysosplenetin B 3,6,7,3'-Tetramethylquercetagetin 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxychromen-4-one 4H-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy- 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,7-trimethoxy-
CAS	603-56-5
EINECS
Chemical Formula	C19H18O8
Molecular Weight	374.34
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Chrysosplenetin Chrysosplenetin MedChemExpress (MCE) HY-N1457 603-56-5 99.68% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Chrysosplenetin Chrysosplenetin MedChemExpress (MCE) HY-N1457 603-56-5 99.68% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3A. CYP3A \| \| \| \| \| \| \| \| \| \| [1]. Ma L, et al. Chrysosplenetin inhibits artemisinin efflux in P-gp-over-expressing Caco-2 cells and reverses P-gp/MDR1 mRNA up-regulated expression induced by artemisinin in mouse small intestine. Pharm Biol. 2017 Dec 55(1):374-380. [Content Brief]
Supplier Website	https://www.medchemexpress.com/chrysosplenetin.html
Last Update	2025-05-21 16:50:25

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