Indole-3-pyruvic acid MedChemExpress (MCE)

Product Name	Indole-3-pyruvic acid
Synonyms	5-iodophthalide indole-3-pyruvic Indole-3-pyruvate Indolyl-3-pyruvate INDOLE PYRUVIC ACID TIMTEC-BB SBB003515 indol-3-ylpyruvicacid Synonyms 5-iodophthalide indole-3-pyruvic Indole-3-pyruvate Indolyl-3-pyruvate INDOLE PYRUVIC ACID TIMTEC-BB SBB003515 indol-3-ylpyruvicacid INDOLE-3-PYRUVIC ACID Indole-3-pyruvic acid indole-3-(2-oxo)-propanoic acid indole-3-pyruvic acid monohydrate 3-(3-Indolyl)-2-Oxopropanoic Acid 3-(1H-indol-3-yl)-2-oxopropanoate alpha-Oxo-1H-indole-3-propanoic acid 3-(1H-indol-3-yl)-2-oxopropanoic acid
CAS	392-12-1
EINECS	206-874-1
Chemical Formula	C11H9NO3
Molecular Weight	203.19
inchi	InChI=1/C11H9NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5H2,(H,14,15)/p-1
Package	10 mM * 1 mL;25 mg;50 mg;100 mg;500 mg
Price	Email to quote
Descriptions	Indole-3-pyruvic acid Indole-3-pyruvic acid MedChemExpress (MCE) HY-W028393 392-12-1 99.79% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Indole-3-pyruvic acid Indole-3-pyruvic acid MedChemExpress (MCE) HY-W028393 392-12-1 99.79% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety. Indole-3-pyruvic acid (50 and 250 μM, 24 h) activates AHR in HepG2 cells[1]. Indole-3-pyruvic acid (50 μM, 4 days) does not inhibit Th1 cell differentiation but promotes Tr1 differentiation[1]. Indole-3-pyruvic acid (1 mM, 24 h) reduces UVB-induced cytotoxicity in HaCaT cells[1]. Indole-3-pyruvic acid (25 mM, 6 h) reduces the levels of COX-2 in HaCaT cells[2]. Indole-3-pyruvic acid (oral administration, fed in MF chow (0.1%) for 5 d) activates AHR in BALB/c mice[1]. Indole-3-pyruvic acid (oral administration, fed in MF chow (0.1%) for 5 wk) abrogates chronic inflammation in a T cell-mediated colitis model[1]. Indole-3-pyruvic acid (100 μM, dose at skin) protects against UVB-induced skin damage in HR-1 hairless mice[2]. Indole-3-pyruvic acid (intraperitoneal injection, 100-200 mg/kg) increases the time spent in the open arms of the elevated plus maze in mice[3]. Microbial Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Reiji Aoki, et al. Indole-3-Pyruvic Acid, an Aryl Hydrocarbon Receptor Activator, Suppresses Experimental Colitis in Mice. J Immunol. 2018 Dec 15 201(12):3683-3693. [Content Brief] [2]. Reiji Aoki, et al. Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. PLoS One. 2014 May 8 9(5):e96804. [Content Brief] [3]. I P Lapin, et al. Anxiolytic effect of indole-3-pyruvic acid (IPA) in mice. Pharmacol Res. 1993 Sep 28(2):129-34. [Content Brief]
Supplier Website	https://www.medchemexpress.com/indole-3-pyruvic-acid.html
Last Update	2025-05-21 16:50:25

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