Blosozumab MedChemExpress (MCE)

Product Name	Blosozumab
Synonyms	Blosozumab
CAS	1132758-87-2
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Blosozumab Blosozumab MedChemExpress (MCE) HY-P99186 1132758-87-2 98.20% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Blosozumab (LY2541546) is an anti-Human sclerostin (SOST) antibody inhibitor. Blosozumab stimulates bone formation and reduces bone resorption. Blosozumab can be used in the research of Osteoporosis. Blosozumab (1-100 mg/kg, i.v.) shows effects of hyperostosis in rats[1]. sclerostin (SOST)[1] In Vivo Blosozumab (1-100 mg/kg, i.v.) shows effects of hyperostosis in rats[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Sprague-Dawley rats [2] Humanized Human IgG4 kappa Human IgG4 (S228P) kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Robert R Recker, et al. A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density. J Bone Miner Res. 2015 Feb Descriptions Blosozumab Blosozumab MedChemExpress (MCE) HY-P99186 1132758-87-2 98.20% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Blosozumab (LY2541546) is an anti-Human sclerostin (SOST) antibody inhibitor. Blosozumab stimulates bone formation and reduces bone resorption. Blosozumab can be used in the research of Osteoporosis. Blosozumab (1-100 mg/kg, i.v.) shows effects of hyperostosis in rats[1]. sclerostin (SOST)[1] In Vivo Blosozumab (1-100 mg/kg, i.v.) shows effects of hyperostosis in rats[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Sprague-Dawley rats [2] Humanized Human IgG4 kappa Human IgG4 (S228P) kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Robert R Recker, et al. A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density. J Bone Miner Res. 2015 Feb 30(2):216-24. [Content Brief] [2]. Daniel G Rudmann, et al. Rat-specific decreases in platelet count caused by a humanized monoclonal antibody against sclerostin. Toxicol Sci. 2012 Feb 125(2):586-94. [Content Brief]
Last Update	2025-04-01 14:45:47

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