EldelumabEldelumab
MedChemExpress (MCE)
HY-P99190
946414-98-8
BMS-936557
MDX-1100
96.76%
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Eldelumab (BMS-936557) is a human anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease.
CXCL10 (IP-10)[1][2]. Clinical Trial
Human
Human IgG1(K214R) kappa
Human IgG1 (K214R) kappa, Isotype Control
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[1]. Gupta RK, et al. Drug repurposing for COVID-19 based on an integrative meta-analysis of SARS-CoV-2 induced gene signature in human airway epithelium. PLoS One. 2021 Sep 28
16(9):e0257784. [Content Brief]
[2]. Asquith DL, et al. Targeting cell migration in rheumatoid arthritis. Curr Opin Rheumatol. 2015 Mar
27(2):204-11. [Content Brief]