Mupadolimab MedChemExpress (MCE)

Product Name	Mupadolimab
Synonyms	Mupadolimab
CAS	2451856-97-4
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Mupadolimab Mupadolimab MedChemExpress (MCE) HY-P99181 2451856-97-4 CPI-006 99.43% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 monoclonal antibody (mAb) that activates CD73POS B cells. Mupadolimab induces the increased expression of markers associated with B cell maturation and antigen presentation, morphologic transformation to plasmablasts, and increased secretion of IgM and IgG[1]. Mupadolimab (10 mg/kg Descriptions Mupadolimab Mupadolimab MedChemExpress (MCE) HY-P99181 2451856-97-4 CPI-006 99.43% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 monoclonal antibody (mAb) that activates CD73POS B cells. Mupadolimab induces the increased expression of markers associated with B cell maturation and antigen presentation, morphologic transformation to plasmablasts, and increased secretion of IgM and IgG[1]. Mupadolimab (10 mg/kg i.p. daily for 15 days) stimulates antigen specific humoral immunity in SARS-CoV-2 infected NSG-SGM3 mice[1]. CD73[1] In Vitro Mupadolimab induces the increased expression of markers associated with B cell maturation and antigen presentation, morphologic transformation to plasmablasts, and increased secretion of IgM and IgG[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Mupadolimab Related Antibodies Humanized Human IgG1 kappa Human IgG1 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Miller R A, et al. Clinical results with a B cell activating anti-CD73 antibody for the immunotherapy of Covid-19. medRxiv, 2021.
Last Update	2025-04-01 14:45:47

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