Basiliximab MedChemExpress (MCE)

Product Name	Unii-9927mt646m
Synonyms	Simulect Bailiximab SDZ-CHI 621 Unii-9927mt646m from USAN List 422 Immunoglobulin G 1 (human-mouse monoclonal chi621 heavy chain anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal chi621 light chain, dimer
CAS	179045-86-4
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	Basiliximab Basiliximab MedChemExpress (MCE) HY-108852 179045-86-4 CHI 621 95.0% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation. Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα[1]. Basiliximab binds only to activated lymphocytes and macrophages/monocytes[3]. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[3]. Basiliximab (CHI 621) (0.07 mg/rat Descriptions Basiliximab Basiliximab MedChemExpress (MCE) HY-108852 179045-86-4 CHI 621 95.0% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti-interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation. Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα[1]. Basiliximab binds only to activated lymphocytes and macrophages/monocytes[3]. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[3]. Basiliximab (CHI 621) (0.07 mg/rat i.v. once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats[2]. Interleukin-2 receptor[1] In Vitro Basiliximab specifically inhibits T lymphocyte proliferation by binding to the IL-2Rα[1]. Basiliximab binds only to activated lymphocytes and macrophages/monocytes[3]. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Basiliximab Related Antibodies Chimeric Human IgG1 kappa Human IgG1 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. McKeage K, et al. Basiliximab: a review of its use as induction therapy in renal transplantation. BioDrugs. 2010 Feb 1 24(1):55-76. [Content Brief] [2]. Cunningham M W, et al. The Role of Interleukin‐2 (IL‐2) in Natural Killer Cell (NK) Activation and Hypertension in a Preclinical Rat Model of Preeclampsia. The FASEB Journal, 2018, 32: 911.1-911.1. [3]. Chapman TM, et al. Basiliximab: a review of its use as induction therapy in renal transplantation. Drugs. 2003 63(24):2803-35. [Content Brief]
Last Update	2025-04-01 14:45:47

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