Bococizumab MedChemExpress (MCE)

Product Name	Bococizumab
Synonyms	Bococizumab
CAS	1407495-02-6
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg
Price	Email to quote
Descriptions	Bococizumab Bococizumab MedChemExpress (MCE) HY-P99187 1407495-02-6 PF-04950615 Descriptions Bococizumab Bococizumab MedChemExpress (MCE) HY-P99187 1407495-02-6 PF-04950615 RN316 99.80% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia. Bococizumab (0-100 mg/kg, i.v.) decreases maternal and fetal cholesterol and does not affect rat embryo-fetal development[2]. PCSK9[1] In Vivo Bococizumab (0-100 mg/kg, i.v.) decreases maternal and fetal cholesterol and does not affect rat embryo-fetal development[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Pregnant Sprague-Dawley (SD) rats[1] Humanized Human IgG2 kappa Human IgG2 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Koutaro Yokote, et al. Efficacy and Safety of Bococizumab (RN316/PF-04950615), a Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, in Hypercholesterolemic Japanese Subjects Receiving a Stable Dose of Atorvastatin or Treatment-Naive - Results From a Randomized, Placebo-Controlled, Dose-Ranging Study. Circ J. 2017 Sep 25 81(10):1496-1505. [Content Brief] [2]. Sarah N Campion, et al. Decreased maternal and fetal cholesterol following maternal bococizumab (anti-PCSK9 monoclonal antibody) administration does not affect rat embryo-fetal development. Regul Toxicol Pharmacol. 2015 Nov 73(2):562-70. [Content Brief]
Last Update	2025-04-01 14:45:47

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