Lenzilumab MedChemExpress (MCE)

Product Name	Lenzilumab
Synonyms	Lenzilumab
CAS	1229575-09-0
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Lenzilumab Lenzilumab MedChemExpress (MCE) HY-P99207 1229575-09-0 KB 003 99.64% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies. Lenzilumab (i.p., 10 mg/kg, daily, 10 days) inhibits GM-CSF without inhibiting the cellular function of CAR-T and enhances its antitumor activity in NSG mice[1]. Human Human IgG1(K214R) kappa Human IgG1 (K214R) kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Rosalie M Sterner, et al. GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood. 2019 Feb 14 Descriptions Lenzilumab Lenzilumab MedChemExpress (MCE) HY-P99207 1229575-09-0 KB 003 99.64% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies. Lenzilumab (i.p., 10 mg/kg, daily, 10 days) inhibits GM-CSF without inhibiting the cellular function of CAR-T and enhances its antitumor activity in NSG mice[1]. Human Human IgG1(K214R) kappa Human IgG1 (K214R) kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Rosalie M Sterner, et al. GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood. 2019 Feb 14 133(7):697-709. [Content Brief] [2]. Zelalem Temesgen, et al. GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia: A Case-Cohort Study. Mayo Clin Proc. 2020 Nov 95(11):2382-2394. [Content Brief]
Last Update	2025-04-01 14:45:47

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