Rilotumumab MedChemExpress (MCE)

Product Name	Rilotumumab
Synonyms	Rilotumumab
CAS	872514-65-3
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Rilotumumab Rilotumumab MedChemExpress (MCE) HY-P99217 872514-65-3 AMG 102 99.10% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Rilotumumab (AMG 102) is an anti-HGF (anti-hepatocyte growth factor) monoclonal antibody, inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research. Rilotumumab (10 μg/mL Descriptions Rilotumumab Rilotumumab MedChemExpress (MCE) HY-P99217 872514-65-3 AMG 102 99.10% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Rilotumumab (AMG 102) is an anti-HGF (anti-hepatocyte growth factor) monoclonal antibody, inhibits HGF/MET-driven signaling. Rilotumumab shows anti-tumor activity, and can be used in castration-resistant prostate cancer (CRPC) and solid tumor research. Rilotumumab (10 μg/mL overnight) shows the decrease of MET phosphorylation at Y1234 and Y1235, and an increase in total MET[2]. Rilotumumab (intraperitoneal injection 1.5 mg/kg once two days 11 d) treatment inhibits glioma cell growth in vivo[2]. Human Human IgG2 kappa Human IgG2 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Ryan CJ, et al. Targeted MET inhibition in castration-resistant prostate cancer: a randomized phase II study and biomarker analysis with rilotumumab plus mitoxantrone and prednisone. Clin Cancer Res. 2013 Jan 1 19(1):215-24. [Content Brief] [2]. Greenall SA, et al. EGFRvIII-mediated transactivation of receptor tyrosine kinases in glioma: mechanism and therapeutic implications. Oncogene. 2015 Oct 8 34(41):5277-87. [Content Brief]
Last Update	2025-04-01 14:45:47

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