Sifalimumab MedChemExpress (MCE)

Product Name	Sifalimumab
Synonyms	Sifalimumab
CAS	1006877-41-3
EINECS
Chemical Formula
Molecular Weight
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	Sifalimumab Sifalimumab MedChemExpress (MCE) HY-P99219 1006877-41-3 MEDI-545 Descriptions Sifalimumab Sifalimumab MedChemExpress (MCE) HY-P99219 1006877-41-3 MEDI-545 MDX 1103 98.55% Please store the product under the recommended conditions in the Certificate of Analysis. Shipping with dry ice. Sifalimumab (MEDI-545) is an anti-IFNα monoclonal antibody. Sifalimumab suppresses the abnormal immune activity by binding to multiple interferon-alpha (IFNα) subtypes. Sifalimumab can be used in systemic lupus erythematosus (SLE) research. Sifalimumab (3-36 μg/well 72 h) attenuates lymphocyte cytotoxicity co-cultured with U-87MG[2]. Sifalimumab (subcutaneous injection 30 mg/kg and 3 μg/g) treatment shows therapeutic effect and attenuates the lymphocyte infiltration[2]. Human Human IgG1 kappa Human IgG1 kappa, Isotype Control \| \| \| \| \| \| \| \| \| \| [1]. Merrill JT, et al. Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Ann Rheum Dis. 2011 Nov 70(11):1905-13. [Content Brief] [2]. La Maestra S, et al. Brain microglia activation induced by intracranial administration of oligonucleotides and its pharmacological modulation. Drug Deliv Transl Res. 2018 Oct 8(5):1345-1354. [Content Brief]
Last Update	2025-04-01 14:45:47

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