(Glu2)-TRH MedChemExpress (MCE)

Product Name	PYR-GLU-PRO-NH2
Synonyms	(GLU2)-TRH;PE-E-P-NH2;PYR-GLU-PRO-NH2;pGlu-Glu-Pro-NH2;PGLU-GLU-PRO AMIDE;PYROGLU-GLU-PRO AMIDE;fertilization promoting peptide;pyroglutamyl-glutamyl-prolineamide
CAS	85541-78-2
EINECS
Chemical Formula	C15H22N4O6
Molecular Weight	354.36
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	(Glu2)-TRH (Glu2)-TRH MedChemExpress (MCE) HY-P3960 85541-78-2 99.68% Sealed storage, away from moisture and light Powder -80°C 2 years -20°C 1 year In solvent : -80°C, 6 months Descriptions (Glu2)-TRH (Glu2)-TRH MedChemExpress (MCE) HY-P3960 85541-78-2 99.68% Sealed storage, away from moisture and light Powder -80°C 2 years -20°C 1 year In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. (Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS. (Glu2)-TRH (1-100 μmol/kg IV) dose-dependently attenuated TRH-induced analeptic action[1]. (Glu2)-TRH (10 μmol/kg IV) 10 min before Pentobarbital (60 mg/kg i.p.) decreases the sleeping time by approximately 20% compared to the vehicle treated group[1]. \| \| \| \| \| \| \| \| \| \| [1]. Vien Nguyen, et al. [Glu2]TRH dose-dependently attenuates TRH-evoked analeptic effect in mice. Brain Res Bull. 2010 Apr 29 82(1-2):83-6. [Content Brief]
Supplier Website	https://www.medchemexpress.com/glu2-trh.html
Last Update	2025-05-21 16:50:25

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