Benzo[a]pyrene-d12 MedChemExpress (MCE)

Product Name	BENZO[A]PYRENE-D12
Synonyms	Benzo[a]pyrene-d12;BENZO[A]PYRENE-D12;3,4-benzopyrene-d12;Perdeuterated benzo[a]pyrene;Benzo[a]pyrene-d12,3,4-Benzopyrene-d12;Benzo[a]pyrene-1,2,3,4,5,6,7,8,9,10,11,12-d12
CAS	63466-71-7
EINECS
Chemical Formula	C20D12
Molecular Weight	264.38
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Benzo[a]pyrene-d12 Benzo[a]pyrene-d12 MedChemExpress (MCE) HY-107377S 63466-71-7 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Benzo[a]pyrene-d12 Benzo[a]pyrene-d12 MedChemExpress (MCE) HY-107377S 63466-71-7 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene[1]. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies[2][3]. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb 53(2):211-216. [Content Brief] [2]. Saeko Onami, et al. Dosimetry for lung tumorigenesis induced by urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P) in A/JJmsSlc mice. J Toxicol Pathol. 2017 Jul 30(3): 209–216. [Content Brief] [3]. Yeo CD, et al. Roflumilast treatment inhibits lung carcinogenesis in benzo(a)pyrene-induced murine lung cancer model. Eur J Pharmacol. 2017 Oct 5812:189 [Content Brief]
Last Update	2025-04-01 14:45:47

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