EDTA-d12 MedChemExpress (MCE)

Product Name	Ethylenediaminetetraacetic-d12 acid
Synonyms	EDTA (D12);ETHYLENEDIAMINETETRAACETIC-D12 ACID;Ethylenediaminetetraacetic-d12 acid;ETHYLENEDIAMINETETRAACETIC ACID (D12)
CAS	203806-08-0
EINECS
Chemical Formula	C10H16N2O8
Molecular Weight	292.24
inchi
Package	5 mg;10 mg
Price	Email to quote
Descriptions	EDTA-d12 EDTA-d12 MedChemExpress (MCE) HY-Y0682S 203806-08-0 Ethylenediaminetetraacetic acid-d12 98.00% 4°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months Descriptions EDTA-d12 EDTA-d12 MedChemExpress (MCE) HY-Y0682S 203806-08-0 Ethylenediaminetetraacetic acid-d12 98.00% 4°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (protect from light, stored under nitrogen) Room temperature in continental US may vary elsewhere. EDTA-d12 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4]. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. \| \| \| \| \| \| \| \| \| \| [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb 53(2):211-216. [Content Brief] [2]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1 412(1):34-9. [Content Brief] [3]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 200745(5):565-76. [Content Brief] [4]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb10(1):58-62. [Content Brief]
Last Update	2025-04-01 14:45:47

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