Acetylcholine iodideAcetylcholine iodide
MedChemExpress (MCE)
HY-101086
2260-50-6
ACh iodide
98.59%
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture and light)
Room temperature in continental US
may vary elsewhere.
Acetylcholine iodide is a muscarinic receptor modulator. Acetylcholine iodide specifically binds to muscarinic receptors, inhibits sodium absorption, and induces chloride secretion. Acetylcholine iodide changes intestinal ion transport, enhances intestinal secretory function, induces or maintains mammary gland development and lactation. Acetylcholine iodide can be used for intestinal ion transport regulation and mammary gland physiological function research.
Acetylcholine iodide (25 mM
added to the serosal fluid of the rat proximal colonic eversion sac) increases the potential difference in the rat proximal colon[2].
Acetylcholine iodide (3 μg
i.v.) increases the electrical potential difference in the proximal colon of rats[2]. Acetylcholine iodide (25 mg/kg
subcutaneous injection
twice a day
15 days) induces mammary ductal growth in some virgin rats[3]. Acetylcholine iodide (25 mg/kg
subcutaneous injection
twice a day
5 days) induces lobular-acinar growth and secretion in the mammary glands of virgin rats pretreated with estrogen[3].
Human Endogenous Metabolite
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[1]. Stavinoha WB, et al. The use of microwave heating to inactivate cholinesterase in the rat brain prior to analysis for acetylcholine. J Neurochem. 1973 Feb
20(2):361-71. [Content Brief]
[2]. Browning JG, et al. The role of acetylcholine in the regulation of ion transport by rat colon mucosa. J Physiol. 1977 Nov
272(3):737-54. [Content Brief]
[3]. MEITES J, et al. Induction and maintenance of mammary growth and lactation in rats with acetylcholine or epinephrine. Proc Soc Exp Biol Med. 1959 Apr
100(4):750-4. [Content Brief]