Fosfomycin sodium MedChemExpress (MCE)

Product Name	phosphomycin disodium salt
Synonyms	2S)-1 Fosfomycin sodium phosphomycin disodium Disodium phosphonomycin Fosfomycin disodium salt phosphomycin disodium salt (3-methyloxiran-2-yl)phosphonic acid Synonyms 2S)-1 Fosfomycin sodium phosphomycin disodium Disodium phosphonomycin Fosfomycin disodium salt phosphomycin disodium salt (3-methyloxiran-2-yl)phosphonic acid Sodium ((2S,3R)-3-methyloxiran-2-yl)phosphonate disodium [(2R,3S)-3-methyloxiran-2-yl]phosphonate (1,2-epoxypropyl)-,disodiumsalt(1r,2s)(-)-phosphonicaci [(2R,3S)-3-Methyloxiran-2-yl]phosphonic acid disodium salt disodium keto-[(2R,3S)-3-methyloxiran-2-yl]-dioxido-phosphorane
CAS	26016-99-9
EINECS	247-409-2
Chemical Formula	C3H8NaO4P
Molecular Weight	162.06
inchi	InChI=1/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1
Package	10 mM * 1 mL;500 mg
Price	Email to quote
Descriptions	Fosfomycin sodium Fosfomycin sodium MedChemExpress (MCE) HY-W016420 26016-99-9 MK-0955 sodium 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Fosfomycin sodium Fosfomycin sodium MedChemExpress (MCE) HY-W016420 26016-99-9 MK-0955 sodium 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Fosfomycin (MK-0955) sodium is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. Fosfomycin sodium is an epoxy antibacterial agent. Compared with other antibacterial agents, it acts by inhibiting the early process of cell wall synthesis[1]. Fosfomycin sodium has bactericidal activity against a variety of gram-negative and gram-positive pathogens, including broad-spectrum production β-Bacteria of lactamase and carbapenemase, and against S. aureus strains with an inhibition rate of 90%[1]. Fosfomycin sodium displays extensive tissue penetration, can be used to research of infections of the CNS, soft tissues, bone, lungs, and abscesses[2]. Fosfomycin sodium (80 mg/kg i.v.-i.v. or i.v.-p.o.) displays the protective effect on the nephrotoxicity of double beckacin, and is not affected by different administration routes[3]. Pharmacokinetic of Fosfomycin sodium in Rats[4] Dibekacin Dose (mg) Vdss (l/kg) β (min-1) T1/2 (min) Urinary recovery (%) 30 0.261 0.0244 28.4 85 \| \| \| \| \| \| \| \| \| \| [1]. Falagas ME, et al. Fosfomycin. Clin Microbiol Rev. 2016 Apr. 29(2):321-47. [Content Brief] [2]. Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31. 6(4):24. [Content Brief] [3]. Inouye S, et al. Protective effect of fosfomycin on the experimental nephrotoxicity induced by dibekacin. J Pharmacobiodyn. 1982 Sep. 5(9):659-69. [Content Brief] [4]. Inouye S, et al. Mode of protective action of fosfomycin against dibekacin-induced nephrotoxicity in the dehydrated rats. J Pharmacobiodyn. 1982 Dec. 5(12):941-50. [Content Brief]
Supplier Website	https://www.medchemexpress.com/fosfomycin-sodium.html
Last Update	2025-05-21 16:50:25

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