Periplocin MedChemExpress (MCE)

Product Name	Periplocoside
Synonyms	Periplocin BRN 0075742 Periplocoside Glucoperiplocymarin Periplogenin + D-cymarose + D-glucose 4-18-00-02439 (Beilstein Handbook Reference) Periplogenin + D-cymarose + D-glucose [German] Synonyms Periplocin BRN 0075742 Periplocoside Glucoperiplocymarin Periplogenin + D-cymarose + D-glucose 4-18-00-02439 (Beilstein Handbook Reference) Periplogenin + D-cymarose + D-glucose [German] (3β,5β)-3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxycard-20(22)-enolide 3β-[(4-O-β-D-Glucopyranosyl-3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-5β,14β-card-20(22)-enolide Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-, (3β,5β)- Card-20(22)-enolide, 3-((2,6-dideoxy-4-O-beta-D-glucopyranosyl-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-, (3-beta,5-beta)-
CAS	13137-64-9
EINECS
Chemical Formula	C36H56O13
Molecular Weight	696.82
inchi	InChI=1/C35H54O13/c1-17-30(48-31-29(41)28(40)27(39)24(15-36)47-31)23(37)13-26(45-17)46-19-4-8-32(2)21-5-9-33(3)20(18-12-25(38)44-16-18)7-11-35(33,43)22(21)6-10-34(32,42)14-19/h12,17,19-24,26-31,36-37,39-43H,4-11,13-16H2,1-3H3/t17-,19+,20-,21+,22-,23+,24-,26+,27-,28+,29-,30-,31+,32-,33-,34+,35+/m1/s1
Package	10 mM * 1 mL;5 mg;10 mg;20 mg
Price	Email to quote
Descriptions	Periplocin Periplocin MedChemExpress (MCE) HY-N1381 13137-64-9 99.92% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Periplocin Periplocin MedChemExpress (MCE) HY-N1381 13137-64-9 99.92% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Periplocin is a cardiotonic steroid isolated from root-bark Periploca sepium Bunge. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase. Periplocin (5-20 μM 48 hours L929 cells) treatment shows increased proliferation up to 131% at 20 μM[1]. Periplocin (5-20 μM 30-120 minutes L929 cells) increases phosphorylation of Src, ERK, PI3K and Akt at active sites in a dosedependent and time-dependent manner. Periplocin (5-20 μM 48 hours) significantly promotes migration of fibroblast cell[1]. Periplocin (5-20 μM 48 hours) increases collagen production in L929 fibroblast[1]. Periplocin induces Na/KATPase mediates the activation of Src/ERK and PI3K/Akt pathways[1]. Periplocin (5-20 mg/kg intraperitoneal injection daily for 14 days female SCID mice) treatment represses the growth of hepatocellular carcinoma (HCC) in xenograft tumor model in mice[2]. Apoptosis[2] In Vitro Periplocin (5-20 μM 48 hours L929 cells) treatment shows increased proliferation up to 131% at 20 μM[1]. Periplocin (5-20 μM 30-120 minutes L929 cells) increases phosphorylation of Src, ERK, PI3K and Akt at active sites in a dosedependent and time-dependent manner. Periplocin (5-20 μM 48 hours) significantly promotes migration of fibroblast cell[1]. Periplocin (5-20 μM 48 hours) increases collagen production in L929 fibroblast[1]. Periplocin induces Na/KATPase mediates the activation of Src/ERK and PI3K/Akt pathways[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Periplocin Related Antibodies Cell Viability Assay[1] Cell Line: L929 cells \| \| \| \| \| \| \| \| \| \| [1]. Chen L, et al. Periplocin promotes wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase. Phytomedicine. 2019 Apr 57:72-83. [Content Brief] [2]. Cheng CF, et al. Antitumor Effect of Periplocin in TRAIL-Resistant Human Hepatocellular Carcinoma Cells through Downregulation of IAPs. Evid Based Complement Alternat Med. 2013 2013:958025. [Content Brief]
Last Update	2025-04-01 14:45:47

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