Diallyl Trisulfide MedChemExpress (MCE)

Product Name	Diallyl trisulfide
Synonyms	AI3-35127 NSC 651936 CCRIS 3251 Allitridin BRN 1745734 FEMA No. 3265 ALLYLTRISULPHIDE Synonyms AI3-35127 NSC 651936 CCRIS 3251 Allitridin BRN 1745734 FEMA No. 3265 ALLYLTRISULPHIDE Allyl trisulfide Dially trisulfide Diallyl trisulfide Diallyl trisulphide Diallyl pertrisulfide Di-2-propenyl trisulfide Trisulfide, di-2-propenyl diprop-2-en-1-yltrisulfane Bis(2-propenyl) trisulfide 1,1'-(Trithio)bis(2-propene) PROP-2-ENYL-TRITHIO PROP-2-ENE Trisulfide, di-2-propenyl (9CI) 3-(allylthio)disulfanylprop-1-ene 3-prop-2-enylsulfanyldisulfanylprop-1-ene 0-01-00-00441 (Beilstein Handbook Reference)
CAS	2050-87-5
EINECS	218-107-8
Chemical Formula	C6H10S3
Molecular Weight	178.34
inchi	InChI=1/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2
Package	10 mM * 1 mL;25 mg;50 mg
Price	Email to quote
Descriptions	Diallyl Trisulfide Diallyl Trisulfide MedChemExpress (MCE) HY-117235 2050-87-5 95.0% -20°C, stored under nitrogen In solvent : -80°C, 6 months Descriptions Diallyl Trisulfide Diallyl Trisulfide MedChemExpress (MCE) HY-117235 2050-87-5 95.0% -20°C, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (stored under nitrogen) Room temperature in continental US may vary elsewhere. Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer. Diallyl Trisulfide (25-100 μM 24-72 h) induces apoptosis and inhibits cell proliferation in A549 cells, exhibiting anticancer activity[1]. Diallyl Trisulfide (5-10 μM 1 h) significantly inhibits naphthalene (20 μM)-stimulated ROS generation and reduces the levels of inflammatory factors IL-6, TNF-α, and IL-8 by increasing superoxide dismutase (SOD) activity, thereby possessing antioxidant and anti-inflammatory activities[2]. Diallyl Trisulfide (93.75-375 µM 24 h) attenuates H9N2 avian influenza virus (AIV) infection in human lung A549 epithelial cells, demonstrating antiviral activity[3]. Diallyl Trisulfide inhibits the growth of Penicillium expansum with antifungal activity (minimum fungicidal concentration (MFC)99 value: ≤ 90 μg/mL)[4]. Diallyl Trisulfide (6 μM/animal Oral gavage, every other day for 30 days) inhibits tumor growth and exhibits anticancer activity in BALB/c nude mice[1]. Diallyl Trisulfide (20-80 mg/kg Oral gavage, single dose) demonstrates antioxidant and anti-inflammatory activities in Kunming mice induced by naphthalene (100 mg/kg orally, single dose)[2]. Diallyl Trisulfide (30 mg/kg intraperitoneal injection once daily for 2 weeks) reduces lung edema and inflammation caused by H9N2 AIV infection in BABL/c mice, exhibiting antiviral activity[3]. IL-6 IL-8 \| \| \| \| \| \| \| \| \| \| [1]. Li W, et al. Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo. Acta Biochim Biophys Sin (Shanghai). 2012 Jul 44(7):577-83. [Content Brief] [2]. Zhang F, et al. Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice. Int Immunopharmacol. 2015 Dec 29(2):326-333. [Content Brief] [3]. Ming L, et al. Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo. Virol J. 2021 Aug 19 18(1):171. [Content Brief] [4]. Pu Liu, et al. Diallyl trisulfide (DATS) effectively induced apoptosis of postharvest diseasePenicillium expansum of citrus. Annals of Microbiology. December 2009, Volume 59, Issue 4, pp 675-679.
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Last Update	2025-05-21 16:50:25

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