α-Arbutin MedChemExpress (MCE)

Product Name	alpha-Arbutin
Synonyms	α-Arbutin a-Arbutin alpha-Arbutin alpha-arbutin Alpha Arbutin Powder Hydroquinone O-α-D-Glucopyranoside 4-Hydroxyphenyl a-D-glucopyranoside Synonyms α-Arbutin a-Arbutin alpha-Arbutin alpha-arbutin Alpha Arbutin Powder Hydroquinone O-α-D-Glucopyranoside 4-Hydroxyphenyl a-D-glucopyranoside 4-Hydroquinone-alpha-D-glucopyranoside 4-hydroquinone-alpha-d-glucopyranoside 4-hydroxyphenyl alpha-D-glucopyranoside (2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL
CAS	84380-01-8
EINECS	209-795-0
Chemical Formula	C12H16O7
Molecular Weight	272.25
inchi	InChI=1/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
Package	10 mM * 1 mL;50 mg;100 mg
Price	Email to quote
Descriptions	α-Arbutin α-Arbutin MedChemExpress (MCE) HY-N3002 84380-01-8 4-Hydroxyphenyl α-D-glucopyranoside 99.98% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions α-Arbutin α-Arbutin MedChemExpress (MCE) HY-N3002 84380-01-8 4-Hydroxyphenyl α-D-glucopyranoside 99.98% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is a tyrosinase inhibitor, which is used as an effective skin whiteners. α-Arbutin is promising for research of various diseases such as hyperpigmentation disorders, types of cancers, central nervous system disorders, osteoporosis, diabetes. α-Arbutin (0.5-2 mM, 1-10 days) significantly inhibits melanin synthesis at noncytotoxic concentrations and reduces cellular tyrosinase activity in HMV-II cells[3]. α-Arbutin (125 and 250 mg/tissue, 13 days) decreases melanin synthesis without affecting cell viability in the three-dimensional cultured skin model[3]. \| \| \| \| \| \| \| \| \| \| [1]. Avonto C, et al. Comparative studies on the chemical and enzymatic stability of alpha- and beta-arbutin.Int J Cosmet Sci. 2016 Apr 38(2):187-93. [Content Brief] [2]. Saeedi M, et al. A comprehensive review of the therapeutic potential of α-arbutin. Phytother Res. 2021 Aug 35(8):4136-4154. [Content Brief] [3]. Sugimoto K, et al. Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model. Biol Pharm Bull. 2004 Apr 27(4):510-4. [Content Brief] [4]. Hazman Ö, et al. Two faces of arbutin in hepatocellular carcinoma (HepG2) cells: Anticarcinogenic effect in high concentration and protective effect against cisplatin toxicity through its antioxidant and anti-inflammatory activity in low concentration[J]. Biologia, 2022, 77(1): 225-239.
Supplier Website	https://www.medchemexpress.com/α-arbutin.html
Last Update	2025-05-21 16:50:25

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