L-Ascorbic acid 2-phosphate MedChemExpress (MCE)

Product Name	L-Ascorbate-2-phosphate
Synonyms	Vitamin C phosphate Ascorbyl-2-phosphate ascorbate-2-phosphate Ascorbyl monophosphate L-Ascorbate-2-phosphate Ascorbic Acid Impurity 6 Ascorbyl-2-monophosphate Synonyms Vitamin C phosphate Ascorbyl-2-phosphate ascorbate-2-phosphate Ascorbyl monophosphate L-Ascorbate-2-phosphate Ascorbic Acid Impurity 6 Ascorbyl-2-monophosphate L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT l-ascorbic acid 2-monophosphate tris-cyclohexylammonium salt [2-(1,2-dihydroxyethyl)-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate
CAS	23313-12-4
EINECS	601-297-5
Chemical Formula	C24H48N3O9P
Molecular Weight	553.64
inchi
Package	100 mg;500 mg;1 g
Price	Email to quote
Descriptions	L-Ascorbic acid 2-phosphate L-Ascorbic acid 2-phosphate MedChemExpress (MCE) HY-103701 23313-12-4 2-Phospho-L-ascorbic acid 37.4% -20°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months Descriptions L-Ascorbic acid 2-phosphate L-Ascorbic acid 2-phosphate MedChemExpress (MCE) HY-103701 23313-12-4 2-Phospho-L-ascorbic acid 37.4% -20°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (protect from light, stored under nitrogen) Room temperature in continental US may vary elsewhere. L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-Ascorbic acid 2-phosphate (0.1-1.5 mM 2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect [1]. L-Ascorbic acid 2-phosphate (50 µM-250 µM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 µM AsA2-P and 10 nM dexamethasone (Dex), and 250 µM AsA2-P and 5 nM Dex[3]. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7 52(12):8711-7. [Content Brief] [2]. Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25 266(15):9997-10003. [Content Brief] [3]. Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15 4(1):17. [Content Brief]
Last Update	2025-04-01 14:45:47

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