2,5-Dihydroxyacetophenone MedChemExpress (MCE)

Product Name	2',5'-Dihydroxyacetophenone
Synonyms	QUINACETOPHENONE Acetylhydroquinone 2-Acetylhydroquinone 2-Acetyl hydroquinone 2,5-Dihydroxyacetophenone 2,5-dihydroxy acetophenone 2',5'-dihydroxy-acetophenon Synonyms QUINACETOPHENONE Acetylhydroquinone 2-Acetylhydroquinone 2-Acetyl hydroquinone 2,5-Dihydroxyacetophenone 2,5-dihydroxy acetophenone 2',5'-dihydroxy-acetophenon 2',5'-Dihydroxyacetophenone 2',5'-Dihydroxy acetophenone 1-Acetyl-2,5-dihydroxybenzene 2,5-Dihydroxy-1-acetylbenzene Acetophenone, 2',5'-dihydroxy- 1-(2,5-dihydroxyphenyl)ethanone 1-(2,5-dihydroxyphenyl)-ethanon 2-AcetylhydroquinoneQuinacetophenone
CAS	490-78-8
EINECS	207-716-4
Chemical Formula	C8H8O3
Molecular Weight	152.15
inchi	InChI=1/C8H8O3/c1-5(9)7-4-6(10)2-3-8(7)11/h2-4,10-11H,1H3
Package	10 mM * 1 mL;100 mg
Price	Email to quote
Descriptions	2,5-Dihydroxyacetophenone 2,5-Dihydroxyacetophenone MedChemExpress (MCE) HY-W001174 490-78-8 99.75% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions 2,5-Dihydroxyacetophenone 2,5-Dihydroxyacetophenone MedChemExpress (MCE) HY-W001174 490-78-8 99.75% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. 2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways. 2,5-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression and significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 via the down-regulation of their mRNA expression in LPS-stimulated RAW264.7 cells. 2,5-Dihydroxyacetophenone potently inhibits the phosphorylation of extracellular signal-related kinase (ERK) 1/2 and the nuclear translocation of nuclear factor-κB (NF-κB) p65 in LPS-stimulated cells[1]. ERK1 ERK2 NF-κB \| \| \| \| \| \| \| \| \| \| [1]. Han Y, et al. 2,5-dihydroxyacetophenone isolated from Rehmanniae Radix Preparata inhibits inflammatoryresponses in lipopolysaccharide-stimulated RAW264.7 macrophages. J Med Food. 2012 Jun 15(6):505-10. [Content Brief]
Supplier Website	https://www.medchemexpress.com/2-5-dihydroxyacetophenone.html
Last Update	2025-05-21 16:50:25

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