α-Solanine MedChemExpress (MCE)

Product Name	Alpha-Solanine
Synonyms	SOLATUNIN a-Solanine SOLATUNINE Alpha-Solanine alpha-SOLANINE tlc POTATOGLYCOALKALOIDS A-solanine from potato sprouts Synonyms SOLATUNIN a-Solanine SOLATUNINE Alpha-Solanine alpha-SOLANINE tlc POTATOGLYCOALKALOIDS A-solanine from potato sprouts alpha-solanin from potato sprouts beta-d-galactopyranoside,(3beta)-solanid-5-en-3-ylo-6-deoxy-alpha-l-mannopyra
CAS	20562-02-1
EINECS	243-879-8
Chemical Formula	C45H73NO15
Molecular Weight	868.07
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	α-Solanine α-Solanine MedChemExpress (MCE) HY-N6602 20562-02-1 99.89% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions α-Solanine α-Solanine MedChemExpress (MCE) HY-N6602 20562-02-1 99.89% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in Solanum nigrum, has been observed to inhibit growth and induce apoptosis in cancer cells. α-Solanine (10-50 µM, 24 h) inhibits the cell viability of JEG-3, inhibits the cell invasion and migration through block of MMP, inhibits the colony formation[2]. α-Solanine (0.5-5 µM, 24 h) inhibits the expression of LPS (HY-D1056)-induced iNOS, COX-2 and pro-inflammatory cytokine like IL-6、TNF-α、IL-1β, inhibits the activation of NF-κB signaling pathway[3]. α-Solanine (10 µM, 24 h) induces autophagy in cancer cell by increasing intracellular ROS levels, activating ER stress, and inhibiting the Akt/mTOR signaling pathway. α-Solanine (5 mg/kg/day, ip for 7 days) exhibits antitumor activity in mouse models[2]. α-Solanine (2.5-10 mg/kg, po., single dose) exhibits anti-inflammtory efficacy in LPS-induced sepsis mouse model[3]. \| \| \| \| \| \| \| \| \| \| [1]. Lei Wang , et al. Inhibitory Effect of α-Solanine on Esophageal Carcinoma in vitro. Exp Ther Med. 2016 Sep 12(3):1525-1530. [Content Brief] [2]. Gu T, et al., α-Solanine Inhibits Proliferation, Invasion, and Migration, and Induces Apoptosis in Human Choriocarcinoma JEG-3 Cells In Vitro and In Vivo. Toxins (Basel). 2021 Mar 13 13(3):210. [Content Brief] [3]. Shin JS, et al., α-Solanine Isolated From Solanum Tuberosum L. cv Jayoung Abrogates LPS-Induced Inflammatory Responses Via NF-κB Inactivation in RAW 264.7 Macrophages and Endotoxin-Induced Shock Model in Mice. J Cell Biochem. 2016 Oct 117(10):2327-39. [Content Brief] [4]. Hasanain M, et al., α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway. Cell Death Dis. 2015 Aug 27 6(8):e1860. [Content Brief]
Supplier Website	https://www.medchemexpress.com/α-solanine.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Glycyl-L-glutamine

Category: Natural Products
CAS: 13115-71-4
Last Update: 2025-05-21 16:50:25

Triose phosphate

Category: Natural Products
CAS: 591-57-1
Last Update: 2025-05-21 16:50:25

Lactyl-CoA

Category: Natural Products
CAS: 1926-57-4
Last Update: 2025-05-21 16:50:25

12(S)-HPETE

Category: Natural Products
CAS: 71774-10-2
Last Update: 2025-05-21 16:50:25

Pyrithiamine

Category: Natural Products
CAS: 534-64-5
Last Update: 2025-05-21 16:50:25

alpha-CEHC

Category: Natural Products
CAS: 4072-32-6
Last Update: 2025-05-21 16:50:25

Maltoheptaose

Category: Natural Products
CAS: 34620-78-5
Last Update: 2025-05-21 16:50:25

Phenoxyethanol

Category: Natural Products
CAS: 122-99-6
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact